# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4580214 | 23 | INH | 0 | ALA4478894 | Active | % | Hepatitis C virus subtype 1b | ||||
2. | ALA3125635 | 70 | Ki | = | 930 | nM | ALA3131504 | 6.03 | nM | Hepatitis C virus subtype 1b | ||
3. | ALA3125634 | 80 | Ki | = | 170 | nM | ALA3131504 | 6.77 | nM | Hepatitis C virus subtype 1b | ||
4. | ALA3125620 | 87 | Ki | = | 740 | nM | ALA3131504 | 6.13 | nM | Hepatitis C virus subtype 1b | ||
5. | Telaprevir | 1, Telaprevir | Ki | = | 6100 | nM | ALA3131504 | 5.21 | nM | Hepatitis C virus subtype 1b | ||
6. | Ciluprevir | BILN-2061 | Ki | = | 120 | nM | ALA3131504 | 6.92 | nM | Hepatitis C virus subtype 1b | ||
7. | ALA3125635 | 70 | Ki | = | 1550 | nM | ALA3131502 | 5.81 | nM | Hepatitis C virus subtype 1b | ||
8. | ALA3125634 | 80 | Ki | = | 420 | nM | ALA3131502 | 6.38 | nM | Hepatitis C virus subtype 1b | ||
9. | ALA3125620 | 87 | Ki | = | 1800 | nM | ALA3131502 | 5.75 | nM | Hepatitis C virus subtype 1b | ||
10. | Telaprevir | 1, Telaprevir | Ki | = | 82 | nM | ALA3131502 | 7.09 | nM | Hepatitis C virus subtype 1b | ||
11. | Ciluprevir | BILN-2061 | Ki | = | 24 | nM | ALA3131502 | 7.62 | nM | Hepatitis C virus subtype 1b | ||
12. | MK-5172 | 15, MK-5172 | IC50 | = | 0.07 | nM | ALA3124059 | 10.15 | nM | Hepatitis C virus subtype 1b | ||
13. | ALA3120488 | 13 | IC50 | = | 0.1 | nM | ALA3124059 | 10.00 | nM | Hepatitis C virus subtype 1b | ||
14. | ALA3120169 | 14 | IC50 | = | 0.18 | nM | ALA3124059 | 9.74 | nM | Hepatitis C virus subtype 1b | ||
15. | ALA3120489 | 15 | IC50 | = | 0.16 | nM | ALA3124059 | 9.80 | nM | Hepatitis C virus subtype 1b | ||
16. | ALA3120490 | 16 | IC50 | = | 0.5 | nM | ALA3124059 | 9.30 | nM | Hepatitis C virus subtype 1b | ||
17. | ALA3120491 | 17 | IC50 | = | 0.27 | nM | ALA3124059 | 9.57 | nM | Hepatitis C virus subtype 1b | ||
18. | ALA3120492 | 18 | IC50 | = | 0.05 | nM | ALA3124059 | 10.30 | nM | Hepatitis C virus subtype 1b | ||
19. | ALA3120493 | 21 | IC50 | = | 0.06 | nM | ALA3124059 | 10.22 | nM | Hepatitis C virus subtype 1b | ||
20. | ALA3120474 | 22 | IC50 | = | 1.31 | nM | ALA3124059 | 8.88 | nM | Hepatitis C virus subtype 1b |