Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Assay	Assay Organism
1.	A 485	A-485	Cell Proliferation EC50		2.341	uM	ALA4886595		uM	Homo sapiens
2.	Sotorasib (AMG510) racemate	(R)-38; AMG-510	IC50	=	355.7	nM	ALA4828614	6.45	nM	Homo sapiens
3.	Sotorasib (AMG510) racemate	(R)-38; AMG-510	IC50	>	10000	nM	ALA4828609		nM	Homo sapiens
4.	Repotrectinib (TPX-0005)	REPOTRECTINIB	IC50	=	5000	nM	ALA4828609	5.30	nM	Homo sapiens
5.	ALA4463075	133	IC50	>	100	uM	ALA4419288		nM	Homo sapiens
6.	ALA4552833	132	IC50	=	60	uM	ALA4419288	4.22	nM	Homo sapiens
7.	ALA4285086	152; PHT7391	IC50	>	100	uM	ALA4419288		nM	Homo sapiens
8.	ALA4288751	151; PHT7390	IC50	>	100	uM	ALA4419288		nM	Homo sapiens
9.	ALA4454755	128	IC50	>	100	uM	ALA4419288		nM	Homo sapiens
10.	ALA4561494	127	IC50	>	100	uM	ALA4419288		nM	Homo sapiens
11.	ALA4442569	126	IC50	=	16	uM	ALA4419288	4.80	nM	Homo sapiens
12.	ALA4577791	125	IC50	=	60	uM	ALA4419288	4.22	nM	Homo sapiens
13.	ALA4472256	124	IC50	=	50	uM	ALA4419288	4.30	nM	Homo sapiens
14.	ALA4474905	100	IC50	>	100	uM	ALA4419288		nM	Homo sapiens
15.	ALA4282142	91; PHT7287	IC50	>	100	uM	ALA4419288		nM	Homo sapiens
16.	ALA4552253	110	IC50	=	28	uM	ALA4419288	4.55	nM	Homo sapiens
17.	ALA4473695	109	IC50	>	100	uM	ALA4419288		nM	Homo sapiens
18.	ALA4515226	108	IC50	=	38	uM	ALA4419288	4.42	nM	Homo sapiens
19.	ALA4529653	107	IC50	=	45	uM	ALA4419288	4.35	nM	Homo sapiens
20.	ALA4451129	106	IC50	=	58	uM	ALA4419288	4.24	nM	Homo sapiens