# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | Doxorubicin hydrochloride | 2 | IC50 | = | 1.5 | uM | ALA5229182 | 5.82 | nM | Homo sapiens | ||
2. | ALA5269134 | 7 | IC50 | = | 5.7 | uM | ALA5229182 | 5.24 | nM | Homo sapiens | ||
3. | ALA5270471 | 6 | IC50 | > | 10 | uM | ALA5229182 | nM | Homo sapiens | |||
4. | ALA5275854 | 1 | IC50 | = | 9.4 | uM | ALA5229182 | 5.03 | nM | Homo sapiens | ||
5. | ALA5192185 | yn-4 | INH | = | 100 | % | ALA5125988 | % | Homo sapiens | |||
6. | ALA5192185 | yn-4 | INH | 0 | ALA5125966 | Active | % | Homo sapiens | ||||
7. | Gefitinib (ZD1839) | Iressa | IC50 | = | 0.863 | uM | ALA5125960 | 6.06 | nM | Homo sapiens | ||
8. | ALA5175849 | E5 | IC50 | = | 7.801 | uM | ALA5125960 | 5.11 | nM | Homo sapiens | ||
9. | ALA5192185 | yn-4 | IC50 | = | 1.891 | uM | ALA5125960 | 5.72 | nM | Homo sapiens | ||
10. | Gefitinib-based PROTAC 3 | PROTAC3 | Activity | 0 | ALA4380798 | Active | Homo sapiens | |||||
11. | Gefitinib (ZD1839) | Iressa | Activity | 0 | ALA4380798 | Active | Homo sapiens | |||||
12. | ALA4442491 | 28; MS154N | Activity | 0 | ALA4380798 | Active | Homo sapiens | |||||
13. | MS154 | 10; MS154 | Activity | 0 | ALA4380798 | Active | Homo sapiens | |||||
14. | ALA4578319 | 27; MS39N | Activity | 0 | ALA4380798 | Active | Homo sapiens | |||||
15. | MS39 | 6; MS39 | Activity | 0 | ALA4380798 | Active | Homo sapiens | |||||
16. | MS154 | 10; MS154 | Activity | 0 | ALA4380754 | Non-Toxic | Homo sapiens | |||||
17. | MS39 | 6; MS39 | Activity | 0 | ALA4380754 | Non-Toxic | Homo sapiens | |||||
18. | ALA4779194 | 9h | Activity | = | 2.66 | % | ALA4771558 | % | Homo sapiens | |||
19. | ALA4779194 | 9h | Activity | = | 8.73 | % | ALA4771557 | % | Homo sapiens | |||
20. | ALA4779194 | 9h | Activity | = | 88.61 | % | ALA4771556 | % | Homo sapiens |