# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5274493 | 201b | IC50 | = | 0.51 | uM | ALA5246240 | 6.29 | nM | Middle East respiratory syndrome-related coronavirus | ||
2. | 4-(cyclopent-1-en-3-ylamino)-5-(2-(4-iodophenyl)hydrazinyl)-4H-1,2,4-triazole-3-thiol | Table 1, R56C1 | IC50 | = | 0.47 | uM | ALA5246240 | 6.33 | nM | Middle East respiratory syndrome-related coronavirus | ||
3. | ALA5280654 | GS-5734 | EC50 | = | 0.074 | uM | ALA5246125 | 7.13 | nM | Middle East respiratory syndrome-related coronavirus | ||
4. | Silvestrol | 13 | EC90 | = | 27 | nM | ALA5235033 | nM | Middle East respiratory syndrome-related coronavirus | |||
5. | Silvestrol | 13 | EC50 | = | 1.3 | nM | ALA5235033 | 8.89 | nM | Middle East respiratory syndrome-related coronavirus | ||
6. | levomepromazine | Levomepromazine | EC50 | = | 2.5 | uM | ALA5234337 | 5.60 | nM | Middle East respiratory syndrome-related coronavirus | ||
7. | Dothiepin hydrochloride | SID56463522 | EC50 | = | 3.4 | uM | ALA5234337 | 5.47 | nM | Middle East respiratory syndrome-related coronavirus | ||
8. | Acetophenazine | Acetophenazine | EC50 | = | 11.2 | uM | ALA5234337 | 4.95 | nM | Middle East respiratory syndrome-related coronavirus | ||
9. | Sotrastaurin | 1 | EC50 | = | 9.7 | uM | ALA5234337 | 5.01 | nM | Middle East respiratory syndrome-related coronavirus | ||
10. | Saracatinib (AZD0530) | 33, AZD-0530 | EC50 | = | 2.9 | uM | ALA5234337 | 5.54 | nM | Middle East respiratory syndrome-related coronavirus | ||
11. | Amodiaquine hydrochloride | AMODIAQUINE DIHYDROCHLORIDE | EC50 | = | 2.1 | uM | ALA5234337 | 5.68 | nM | Middle East respiratory syndrome-related coronavirus | ||
12. | Hydroxyzine | hydroxyzine | EC50 | = | 14.4 | uM | ALA5234337 | 4.84 | nM | Middle East respiratory syndrome-related coronavirus | ||
13. | ALA211045 | SID29217606 | EC50 | = | 36.9 | uM | ALA5234337 | 4.43 | nM | Middle East respiratory syndrome-related coronavirus | ||
14. | Lopinavir | 1a, ABT-378 Lopinavir | EC50 | = | 8 | uM | ALA5234334 | 5.10 | nM | Middle East respiratory syndrome-related coronavirus | ||
15. | loperamide | Loperamide | EC50 | = | 4.8 | uM | ALA5234334 | 5.32 | nM | Middle East respiratory syndrome-related coronavirus | ||
16. | Chlorpromazine | cholrpromazine | EC50 | = | 4.9 | uM | ALA5234334 | 5.31 | nM | Middle East respiratory syndrome-related coronavirus | ||
17. | Chloroquine | Chloroquine | EC50 | = | 3 | uM | ALA5234334 | 5.52 | nM | Middle East respiratory syndrome-related coronavirus | ||
18. | Remdesivir | 4b | IC50 | = | 0.025 | uM | ALA5231838 | 7.60 | nM | Middle East respiratory syndrome-related coronavirus | ||
19. | Dasatinib | 2, BMS-354825 | EC50 | = | 5.4 | uM | ALA5231837 | 5.27 | nM | Middle East respiratory syndrome-related coronavirus | ||
20. | Gemcitabine | Gemzar | EC50 | = | 1.2 | uM | ALA5231837 | 5.92 | nM | Middle East respiratory syndrome-related coronavirus |