| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  Calpain inhibitor II | 2 | EC50 | = | 2.07 | uM | ALA5247345 | 5.68 | nM | Severe acute respiratory syndrome-related coronavirus | ||
| 2. |  ALA5266148 | Calpain inhibitors XII | EC50 | = | 0.49 | uM | ALA5247345 | 6.31 | nM | Severe acute respiratory syndrome-related coronavirus | ||
| 3. |  ALA5271613 | 115 | EC50 | = | 18 | uM | ALA5247342 | 4.75 | nM | Severe acute respiratory syndrome-related coronavirus | ||
| 4. |  ALA5267356 | 26 | EC50 | = | 2.883 | uM | ALA5247342 | 5.54 | nM | Severe acute respiratory syndrome-related coronavirus | ||
| 5. |  ALA4852855 | TG-0205221 | EC50 | = | 0.6 | uM | ALA5247337 | 6.22 | nM | Severe acute respiratory syndrome-related coronavirus | ||
| 6. |  MPro 13b | 30 | EC50 | = | 1.75 | uM | ALA5247313 | 5.76 | nM | Severe acute respiratory syndrome-related coronavirus | ||
| 7. |  (S)-N-Benzyl-3-((S)-2-cinnamamido-3-cyclohexylpropanamido)-2-oxo-4-((S)-2-oxopyrrolidin-3-yl)butanamide | 11r | EC50 | = | 1.4 | uM | ALA5247313 | 5.85 | nM | Severe acute respiratory syndrome-related coronavirus | ||
| 8. |  ALA4590737 | 11n | EC50 | = | 7.2 | uM | ALA5247313 | 5.14 | nM | Severe acute respiratory syndrome-related coronavirus | ||
| 9. |  ALA4442435 | 11s | EC50 | = | 1.9 | uM | ALA5247313 | 5.72 | nM | Severe acute respiratory syndrome-related coronavirus | ||
| 10. |  ALA5287375 | BCX4430 | EC50 | > | 100 | uM | ALA5246131 | nM | Severe acute respiratory syndrome-related coronavirus | |||
| 11. |  Ribavirin | Ribavirin | EC50 | > | 100 | uM | ALA5246131 | nM | Severe acute respiratory syndrome-related coronavirus | |||
| 12. |  Favipiravir | T-705 | EC50 | = | 61.88 | uM | ALA5246130 | 4.21 | nM | Severe acute respiratory syndrome-related coronavirus | ||
| 13. |  ALA5280654 | GS-5734 | EC50 | = | 0.069 | uM | ALA5246126 | 7.16 | nM | Severe acute respiratory syndrome-related coronavirus | ||
| 14. | ALA5280654 | GS-5734 | EC90 | = | 1.76 | uM | ALA5246113 | uM | Severe acute respiratory syndrome-related coronavirus | |||
| 15. |  Chloroquine | Chloroquine | EC50 | = | 1.13 | uM | ALA5246113 | 5.95 | nM | Severe acute respiratory syndrome-related coronavirus | ||
| 16. |  Saracatinib (AZD0530) | 33, AZD-0530 | EC50 | = | 2.4 | uM | ALA5234339 | 5.62 | nM | Severe acute respiratory syndrome-related coronavirus | ||
| 17. |  Lopinavir | 1a, ABT-378 Lopinavir | EC50 | = | 17.1 | uM | ALA5234335 | 4.77 | nM | Severe acute respiratory syndrome-related coronavirus | ||
| 18. |  loperamide | Loperamide | EC50 | = | 5.9 | uM | ALA5234335 | 5.23 | nM | Severe acute respiratory syndrome-related coronavirus | ||
| 19. |  Chlorpromazine | cholrpromazine | EC50 | = | 8.8 | uM | ALA5234335 | 5.06 | nM | Severe acute respiratory syndrome-related coronavirus | ||
| 20. | Chloroquine | Chloroquine | EC50 | = | 4.1 | uM | ALA5234335 | 5.39 | nM | Severe acute respiratory syndrome-related coronavirus |
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