# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2436454 | 12 | INH | 0 | ALA2439432 | Active | % | Homo sapiens | ||||
2. | ALA2436446 | 36 | INH | 0 | ALA2439432 | Active | % | Homo sapiens | ||||
3. | 3-Bromo-6-chloroimidazo[1,2-b]pyridazine | 27 | INH | 0 | ALA2439432 | Active | % | Homo sapiens | ||||
4. | R406 (free base) | 5, R-406 | Kd | = | 11 | nM | ALA2438984 | 7.96 | nM | Homo sapiens | ||
5. | Foretinib (GSK1363089) | EXEL-2880/GSK-1363089 | Kd | = | 340 | nM | ALA2438984 | 6.47 | nM | Homo sapiens | ||
6. | Staurosporine (DMSO solution) | 1 (Staurosporine) | Kd | = | 20 | nM | ALA2438984 | 7.70 | nM | Homo sapiens | ||
7. | 5-[5-(3,4,5-trimethoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]-1H-indole | 8 | IC50 | = | 3 | nM | ALA2437703 | 8.52 | nM | Homo sapiens | ||
8. | ALA502835 | 3, BIBF1120 | Kd | = | 700 | nM | ALA2438984 | 6.16 | nM | Homo sapiens | ||
9. | CEP-1347 | 2 | IC50 | = | 6 | nM | ALA2438999 | 8.22 | nM | Homo sapiens | ||
10. | Tozasertib | VX-680 | Kd | = | 680 | nM | ALA2438984 | 6.17 | nM | Homo sapiens | ||
11. | ALA2436982 | 10 | IC50 | = | 7 | nM | ALA2437703 | 8.15 | nM | Homo sapiens | ||
12. | Lestaurtinib | CEP-701 | Kd | = | 18 | nM | ALA2438984 | 7.75 | nM | Homo sapiens | ||
13. | ALA2436976 | 12 | IC50 | = | 9 | nM | ALA2437703 | 8.05 | nM | Homo sapiens | ||
14. | ALA608533 | PKC-412 | Kd | = | 17 | nM | ALA2438984 | 7.77 | nM | Homo sapiens | ||
15. | URMC-099 | 1, URMC-099 | IC50 | = | 14 | nM | ALA2437703 | 7.85 | nM | Homo sapiens | ||
16. | KW-2449 | KW-2449 | Kd | = | 230 | nM | ALA2438984 | 6.64 | nM | Homo sapiens | ||
17. | TAE684 (NVP-TAE684) | 12, NVP-TAE684 | Kd | = | 420 | nM | ALA2438984 | 6.38 | nM | Homo sapiens | ||
18. | ALA2436981 | 9 | IC50 | = | 19 | nM | ALA2437703 | 7.72 | nM | Homo sapiens | ||
19. | ALA2436977 | 13 | IC50 | = | 21 | nM | ALA2437703 | 7.68 | nM | Homo sapiens | ||
20. | URMC-099 | 1, URMC-099 | INH | > | 50 | % | ALA2439783 | % | Homo sapiens |