# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4475619 | 18 | INH | 0 | ALA4394900 | Active | % | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | ||||
2. | ALA4476230 | 19 | INH | = | 53 | % | ALA4394899 | % | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | |||
3. | ALA4559996 | 6 | IC50 | = | 196.5 | nM | ALA4394894 | 6.71 | nM | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | ||
4. | 5'-Amino-5'-deoxyadenosine | 1 | IC50 | = | 8 | uM | ALA4394894 | 5.10 | nM | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | ||
5. | ALA388931 | table 1 | IC50 | = | 2.3 | uM | ALA4394894 | 5.64 | nM | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | ||
6. | Sangivamycin | 19 | IC50 | = | 16.5 | uM | ALA4394894 | 4.78 | nM | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | ||
7. | 5-Iodotubercidin | 1s | IC50 | = | 1.2 | uM | ALA4394894 | 5.92 | nM | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | ||
8. | ALA4475619 | 18 | Ki | = | 5.3 | nM | ALA4394894 | 8.28 | nM | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | ||
9. | ALA4474951 | 17 | Ki | = | 48 | nM | ALA4394894 | 7.32 | nM | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | ||
10. | ALA4463459 | 16 | Ki | = | 32.6 | nM | ALA4394894 | 7.49 | nM | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | ||
11. | ALA4458246 | 15 | Ki | = | 27.5 | nM | ALA4394894 | 7.56 | nM | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | ||
12. | ALA4442160 | 14 | Ki | = | 25.5 | nM | ALA4394894 | 7.59 | nM | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | ||
13. | ALA4539148 | 13 | Ki | = | 23 | nM | ALA4394894 | 7.64 | nM | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | ||
14. | ALA4525944 | 12 | Ki | = | 21.3 | nM | ALA4394894 | 7.67 | nM | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | ||
15. | ALA4449169 | 11 | Ki | = | 19.9 | nM | ALA4394894 | 7.70 | nM | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | ||
16. | ALA4566815 | 10 | Ki | = | 18.9 | nM | ALA4394894 | 7.72 | nM | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | ||
17. | ALA4475059 | 9 | Ki | = | 18.5 | nM | ALA4394894 | 7.73 | nM | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | ||
18. | ALA4448092 | 8 | Ki | = | 16.3 | nM | ALA4394894 | 7.79 | nM | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | ||
19. | ALA2042164 | 9 | Ki | = | 120.2 | nM | ALA4394894 | 6.92 | nM | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |