# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4573907 | 53 | Ratio IC50 | = | 5.7 | ALA4392460 | Rattus norvegicus | |||||
2. | ALA4573907 | 53 | Ratio IC50 | = | 3 | ALA4392458 | Rattus norvegicus | |||||
3. | ALA4573907 | 53 | IC50 | = | 19.5 | uM | ALA4392455 | 4.71 | nM | Rattus norvegicus | ||
4. | Atazanavir | 25b | IC50 | = | 3.4 | uM | ALA4392455 | 5.47 | nM | Rattus norvegicus | ||
5. | ALA4573907 | 53 | IC50 | = | 12.6 | uM | ALA4392453 | 4.90 | nM | Rattus norvegicus | ||
6. | Atazanavir | 25b | IC50 | = | 4.2 | uM | ALA4392453 | 5.38 | nM | Rattus norvegicus | ||
7. | Regorafenib (BAY 73-4506) | 2, BAY-734506 | INH | 0 | ALA4316687 | Active | % | Rattus norvegicus | ||||
8. | Regorafenib (BAY 73-4506) | 2, BAY-734506 | INH | 0 | ALA4316676 | Active | % | Rattus norvegicus | ||||
9. | Regorafenib (BAY 73-4506) | 2, BAY-734506 | INH | = | 96 | % | ALA4316685 | % | Rattus norvegicus | |||
10. | Regorafenib (BAY 73-4506) | 2, BAY-734506 | INH | = | 89 | % | ALA4316686 | % | Rattus norvegicus | |||
11. | ALA4474105 | 6; 8-OH-6TP | Ki | > | 100 | uM | ALA4316664 | nM | Rattus norvegicus | |||
12. | 6-Thioxanthine | TX | Ki | > | 100 | uM | ALA4316664 | nM | Rattus norvegicus | |||
13. | ALA3544573 | 6TU | Ki | > | 100 | uM | ALA4316664 | nM | Rattus norvegicus | |||
14. | Mercaptopurine (6-MP) | 1 | Ki | > | 100 | uM | ALA4316664 | nM | Rattus norvegicus | |||
15. | ALA3544573 | 6TU | INH | 0 | ALA4316679 | Not Active | % | Rattus norvegicus | ||||
16. | Mercaptopurine (6-MP) | 1 | INH | 0 | ALA4316679 | Not Active | % | Rattus norvegicus | ||||
17. | ALA3544573 | 6TU | INH | 0 | ALA4316678 | Not Active | % | Rattus norvegicus | ||||
18. | Mercaptopurine (6-MP) | 1 | INH | 0 | ALA4316678 | Not Active | % | Rattus norvegicus | ||||
19. | ALA3544573 | 6TU | INH | 0 | ALA4316677 | Not Active | % | Rattus norvegicus | ||||
20. | Mercaptopurine (6-MP) | 1 | INH | 0 | ALA4316677 | Not Active | % | Rattus norvegicus |