Activities

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Activities

Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA5190836	37, Mixtureofdiastereomers	INH	=	40	%	ALA5131161			%	Plasmodium falciparum (isolate 3D7)
2.	WM382	WM382	IC50	=	0.03	nM	ALA5131159	10.52		nM	Plasmodium falciparum (isolate 3D7)
3.	ALA5199100	40	IC50	=	0.4	nM	ALA5131159	9.40		nM	Plasmodium falciparum (isolate 3D7)
4.	ALA5207556	39	IC50	=	0.6	nM	ALA5131159	9.22		nM	Plasmodium falciparum (isolate 3D7)
5.	ALA5193119	38	IC50	=	0.3	nM	ALA5131159	9.52		nM	Plasmodium falciparum (isolate 3D7)
6.	ALA5187792	36	IC50	=	0.07	nM	ALA5131159	10.15		nM	Plasmodium falciparum (isolate 3D7)
7.	ALA5182418	35	IC50	=	0.06	nM	ALA5131159	10.22		nM	Plasmodium falciparum (isolate 3D7)
8.	ALA5178733	(R)-WM5	IC50	=	5.7	nM	ALA5131159	8.24		nM	Plasmodium falciparum (isolate 3D7)
9.	ALA5197877	(R)-WM4	IC50	=	1.9	nM	ALA5131159	8.72		nM	Plasmodium falciparum (isolate 3D7)
10.	ALA4449532	(S,R)-4c	INH		0		ALA4331654		Active	%	Plasmodium falciparum (isolate 3D7)
11.	ALA2334376	33	INH		0		ALA4331654		Active	%	Plasmodium falciparum (isolate 3D7)
12.	ALA4475791	(S,R)-2a	INH		0		ALA4331654		Active	%	Plasmodium falciparum (isolate 3D7)
13.	ALA4449532	(S,R)-4c	INH		0		ALA4331653		Active	%	Plasmodium falciparum (isolate 3D7)
14.	ALA2334376	33	INH		0		ALA4331653		Active	%	Plasmodium falciparum (isolate 3D7)
15.	ALA5190700	UCB7362	IC50	=	7	nM	ALA5112394	8.15		nM	Plasmodium falciparum (isolate 3D7)
16.	ALA5190700	UCB7362	IC90	=	52	nM	ALA5112370			nM	Plasmodium falciparum (isolate 3D7)
17.	ALA5190700	UCB7362	IC50	=	7	nM	ALA5112370	8.15		nM	Plasmodium falciparum (isolate 3D7)
18.	ALA5204856	5	IC50	=	32	nM	ALA5112370	7.50		nM	Plasmodium falciparum (isolate 3D7)
19.	ALA5204196	4	IC50	=	9	nM	ALA5112370	8.05		nM	Plasmodium falciparum (isolate 3D7)
20.	ALA5191783	3	IC90	=	72	nM	ALA5112370			nM	Plasmodium falciparum (isolate 3D7)