# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | CX-4945 (Silmitasertib) | 25n | INH | 0 | ALA5251706 | Active | % | Homo sapiens | ||||
2. | ALA269538 | 1 | INH | 0 | ALA5251706 | Active | % | Homo sapiens | ||||
3. | 1-Azakenpaullone | 16 (1-Azakenpaullone) | INH | 0 | ALA5251703 | Active | % | Homo sapiens | ||||
4. | ALA269538 | 1 | INH | 0 | ALA5251703 | Active | % | Homo sapiens | ||||
5. | CX-4945 (Silmitasertib) | 25n | INH | = | 100 | % | ALA5251703 | % | Homo sapiens | |||
6. | 1-Azakenpaullone | 16 (1-Azakenpaullone) | Tm | = | 2 | degrees C | ALA5251701 | degrees C | Homo sapiens | |||
7. | ALA269538 | 1 | Tm | = | 10.5 | degrees C | ALA5251701 | degrees C | Homo sapiens | |||
8. | CX-4945 (Silmitasertib) | 25n | Tm | = | 12 | degrees C | ALA5251701 | degrees C | Homo sapiens | |||
9. | 1-Azakenpaullone | 16 (1-Azakenpaullone) | IC50 | 0 | ALA5251699 | Not Active | Homo sapiens | |||||
10. | ALA269538 | 1 | IC50 | = | 0.27 | uM | ALA5251699 | 6.57 | nM | Homo sapiens | ||
11. | CX-4945 (Silmitasertib) | 25n | IC50 | = | 0.16 | uM | ALA5251699 | 6.80 | nM | Homo sapiens | ||
12. | CX-4945 (Silmitasertib) | 25n | Kd(app) | = | 35 | nM | ALA5251697 | 7.46 | nM | Homo sapiens | ||
13. | 1-Azakenpaullone | 16 (1-Azakenpaullone) | Activity | 0 | ALA5251693 | Not Active | Homo sapiens | |||||
14. | ALA269538 | 1 | Kd | = | 13.4 | nM | ALA5251692 | 7.87 | nM | Homo sapiens | ||
15. | CX-4945 (Silmitasertib) | 25n | Kd | = | 1.8 | nM | ALA5251692 | 8.74 | nM | Homo sapiens | ||
16. | ALA5286716 | 37; Cpd C17 | INH | 0 | ALA5251391 | Not Active | % | Homo sapiens | ||||
17. | ALA1997924 | SID103905272 | INH | 0 | ALA5251391 | Not Active | % | Homo sapiens | ||||
18. | PIK-75, free base | 1 | INH | 0 | ALA5251391 | Not Active | % | Homo sapiens | ||||
19. | ALA4873449 | 8h | INH | 0 | ALA5251391 | Not Active | % | Homo sapiens | ||||
20. | ALA5086263 | 10 | INH | 0 | ALA5251391 | Not Active | % | Homo sapiens |