# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | Pyruvic acid | 1 | Activity | 0 | ALA5260791 | Dose-Dependent Effect | Mycobacterium tuberculosis | |||||
2. | ALA3823497 | 25 | IC50 | = | 10.9 | uM | ALA5260790 | 4.96 | nM | Mycobacterium tuberculosis | ||
3. | ALA3823834 | 26 | IC50 | = | 6.6 | uM | ALA5260790 | 5.18 | nM | Mycobacterium tuberculosis | ||
4. | Oxalacetic acid | Oxaloacetate | Kcat/Km | = | 24 | /min/microM | ALA5260781 | /min/microM | Mycobacterium tuberculosis | |||
5. | Oxalacetic acid | Oxaloacetate | Kcat | = | 340 | /min | ALA5260780 | /min | Mycobacterium tuberculosis | |||
6. | Oxalacetic acid | Oxaloacetate | Vmax | = | 3.4 | microM/min | ALA5260779 | microM/min | Mycobacterium tuberculosis | |||
7. | Oxalacetic acid | Oxaloacetate | Km(app) | = | 14.3 | uM | ALA5260778 | nM | Mycobacterium tuberculosis | |||
8. | Pyruvic acid | 1 | deltaTm | = | 12.32 | degrees C | ALA5260771 | degrees C | Mycobacterium tuberculosis | |||
9. | Oxalacetic acid | Oxaloacetate | deltaTm | = | 12.32 | degrees C | ALA5260770 | degrees C | Mycobacterium tuberculosis | |||
10. | Polyglycolide | glycolic acid | deltaTm | = | 0.15 | degrees C | ALA5260769 | degrees C | Mycobacterium tuberculosis | |||
11. | Glyoxylic acid solution | glyoxylate | deltaTm | = | 0.1 | degrees C | ALA5260769 | degrees C | Mycobacterium tuberculosis | |||
12. | ALA1230762 | Acetoacetate | deltaTm | = | 0.19 | degrees C | ALA5260769 | degrees C | Mycobacterium tuberculosis | |||
13. | Oxalacetic acid | Oxaloacetate | deltaTm | = | 11.16 | degrees C | ALA5260769 | degrees C | Mycobacterium tuberculosis | |||
14. | Pyruvic acid | 1 | deltaTm | = | 2.31 | degrees C | ALA5260769 | degrees C | Mycobacterium tuberculosis |