# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | Bictegravir | BICTEGRAVIR | EC50 | <= | 5 | nM | ALA5237329 | nM | Human immunodeficiency virus 1 | |||
2. | Bictegravir | BICTEGRAVIR | EC50 | <= | 5 | nM | ALA5237328 | nM | Human immunodeficiency virus 1 | |||
3. | Bictegravir | BICTEGRAVIR | EC50 | <= | 5 | nM | ALA5237327 | nM | Human immunodeficiency virus 1 | |||
4. | Dolutegravir (GSK1349572) | DOLUTEGRAVIR | IC50 | = | 0.68 | nM | ALA5237323 | 9.17 | nM | Human immunodeficiency virus 1 | ||
5. | ALA3125972 | 8c | IC50 | = | 550 | nM | ALA5237320 | 6.26 | nM | Human immunodeficiency virus 1 | ||
6. | ALA3125971 | 8b | IC50 | = | 400 | nM | ALA5237320 | 6.40 | nM | Human immunodeficiency virus 1 | ||
7. | ALA3125970 | 8a | IC50 | = | 270 | nM | ALA5237320 | 6.57 | nM | Human immunodeficiency virus 1 | ||
8. | ALA3125981 | 7c | IC50 | = | 410 | nM | ALA5237320 | 6.39 | nM | Human immunodeficiency virus 1 | ||
9. | ALA3125980 | 7b | IC50 | = | 170 | nM | ALA5237320 | 6.77 | nM | Human immunodeficiency virus 1 | ||
10. | ALA3125979 | 7a | IC50 | = | 140 | nM | ALA5237320 | 6.85 | nM | Human immunodeficiency virus 1 | ||
11. | ALA3125978 | 6c | IC50 | = | 1800 | nM | ALA5237320 | 5.75 | nM | Human immunodeficiency virus 1 | ||
12. | ALA3125977 | 6b | IC50 | = | 780 | nM | ALA5237320 | 6.11 | nM | Human immunodeficiency virus 1 | ||
13. | ALA3125976 | 6a | IC50 | = | 530 | nM | ALA5237320 | 6.28 | nM | Human immunodeficiency virus 1 | ||
14. | Elvitegravir (GS-9137, JTK-303) | 12 | IC50 | = | 7.2 | nM | ALA5237320 | 8.14 | nM | Human immunodeficiency virus 1 | ||
15. | Oseltamivir Acid | 1 (GS-4071) | IC50 | = | 0.01 | uM | ALA5167159 | 8.00 | nM | Human immunodeficiency virus 1 | ||
16. | ALA5187320 | 24 | IC50 | = | 10.6 | uM | ALA5167159 | 4.97 | nM | Human immunodeficiency virus 1 | ||
17. | ALA437708 | 4a | IC50 | = | 0.085 | uM | ALA5163712 | 7.07 | nM | Human immunodeficiency virus 1 | ||
18. | Raltegravir (MK-0518) | 1, raltegravir | IC50 | = | 0.015 | uM | ALA5163705 | 7.82 | nM | Human immunodeficiency virus 1 | ||
19. | Raltegravir (MK-0518) | 1, raltegravir | INH | = | 85.32 | % | ALA5157622 | % | Human immunodeficiency virus 1 | |||
20. | ALA5194261 | 4e | INH | = | 9.58 | % | ALA5157619 | % | Human immunodeficiency virus 1 |