| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA5276374 | (S)-20a; BGB-8035 | IC50 | = | 94 | nM | ALA5251919 | 7.03 | nM | Homo sapiens | ||
| 2. |  ALA5286014 | 10; TAS0728 | IC50 | = | 8.5 | nM | ALA5243473 | 8.07 | nM | Homo sapiens | ||
| 3. |  mobocertinib | MOBOCERTINIB | INH | > | 97 | % | ALA5238871 | % | Homo sapiens | |||
| 4. |  Neratinib (HKI-272) | 25o (table 3) | IC50 | = | 19 | nM | ALA5233315 | 7.72 | nM | Homo sapiens | ||
| 5. |  Afatinib dimaleate | AFATINIB DIMALEATE | IC50 | = | 14 | nM | ALA5214832 | 7.85 | nM | Homo sapiens | ||
| 6. |  Acalabrutinib (ACP-196) | ACALABRUTINIB | IC50 | = | 16 | nM | ALA5213042 | 7.80 | nM | Homo sapiens | ||
| 7. | Acalabrutinib (ACP-196) | ACALABRUTINIB | % of control | = | 4.3 | % | ALA5213041 | % | Homo sapiens | |||
| 8. |  Zanubrutinib (BGB-3111) | BDBM250082 | IC50 | = | 1.58 | nM | ALA5210352 | 8.80 | nM | Homo sapiens | ||
| 9. | Afatinib dimaleate | AFATINIB DIMALEATE | Kd | = | 6.3 | nM | ALA5210627 | 8.20 | nM | Homo sapiens | ||
| 10. | Zanubrutinib (BGB-3111) | BDBM250082 | IC50 | = | 360 | nM | ALA5209937 | 6.44 | nM | Homo sapiens | ||
| 11. | Afatinib dimaleate | AFATINIB DIMALEATE | IC50 | = | 1437 | nM | ALA5210116 | 5.84 | nM | Homo sapiens | ||
| 12. |  ALA5175977 | 28 | IC50 | > | 10 | uM | ALA5165277 | nM | Homo sapiens | |||
| 13. |  PF-543 | PF-543 | IC50 | > | 10 | uM | ALA5165277 | nM | Homo sapiens | |||
| 14. |  Afatinib | BIBW-2992 | IC50 | = | 7.2 | nM | ALA5161061 | 8.14 | nM | Homo sapiens | ||
| 15. |  ALA5208454 | C6 | IC50 | = | 2 | nM | ALA5161061 | 8.70 | nM | Homo sapiens | ||
| 16. |  ALA5182567 | C5 | IC50 | = | 1.6 | nM | ALA5161061 | 8.80 | nM | Homo sapiens | ||
| 17. |  ALA5169523 | 25 | INH | = | 94 | % | ALA5156286 | % | Homo sapiens | |||
| 18. |  ALA5188399 | 1 | Activity | <= | 70 | % | ALA5155253 | % | Homo sapiens | |||
| 19. |  4-(6-((4-Ethynylpyrimidin-2-yl)Ethynyl)-1H-Benzo[d]Imidazol-1-yl)Pyrimidin-2-Amine | 18 | INH | > | 50 | % | ALA5151678 | % | Homo sapiens | |||
| 20. |  ALA2110732 | 5 | IC50 | = | 73.7 | nM | ALA5150421 | 7.13 | nM | Homo sapiens |
The page will load shortly, Thanks for your patience!