Activities

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Activities

Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA1580091	SID17433188	IC50	=	0.42	uM	ALA2412647	6.38		nM	Homo sapiens
2.	(5-amino-3-pyridin-3-yl-1,2,4-triazol-1-yl)-(4-methylphenyl)methanone	SID14731064	IC50	=	0.57	uM	ALA2412647	6.24		nM	Homo sapiens
3.	ALA1464269	SID24823247	IC50	>	30	uM	ALA2412647			nM	Homo sapiens
4.	ALA1471674	SID4259904	IC50	>	30	uM	ALA2412647			nM	Homo sapiens
5.	ALA1580446	SID14726717	IC50	>	30	uM	ALA2412647			nM	Homo sapiens
6.	(5-amino-3-pyridin-3-yl-1,2,4-triazol-1-yl)-(4-methylphenyl)methanone	SID14731064	t1/2	=	5	min	ALA2412633			hr	Homo sapiens
7.	ALA1580091	SID17433188	t1/2	=	5	min	ALA2412633			hr	Homo sapiens
8.	ALA2407437	2	IC50		0		ALA2412647		Not Active		Homo sapiens
9.	ALA1538801	SID17414481	IC50		0		ALA2412647		Not Active		Homo sapiens
10.	ALA2089125	6	Ki	=	457	nM	ALA2090834	6.34		nM	Homo sapiens
11.	ALA2089121	2, 3:2 diastereomeric mixure	Ki	=	6124	nM	ALA2090834	5.21		nM	Homo sapiens
12.	ALA2089154	7	Ki	=	4.6	nM	ALA2090833	8.34		nM	Homo sapiens
13.	ALA2089124	5	Ki	=	1.4	nM	ALA2090833	8.85		nM	Homo sapiens
14.	ALA2089123	4	Ki	=	0.088	nM	ALA2090833	10.06		nM	Homo sapiens
15.	ALA2089122	3	Ki	=	9.5	nM	ALA2090833	8.02		nM	Homo sapiens
16.	inhibitor 1 [Colombo et al., 2012]	1	Ki	=	0.011	nM	ALA2090833	10.96		nM	Homo sapiens
17.	inhibitor 1 [Colombo et al., 2012]	1	INH		0		ALA2090832		Active	%	Homo sapiens
18.	ALA1767120	i-uPA, Glu-Gly-Arg-chloromethyl ketone	INH		0		ALA2090831		Active	%	Homo sapiens
19.	inhibitor 1 [Colombo et al., 2012]	1	INH		0		ALA2090397		Active	%	Homo sapiens
20.	ALA3289302	2	Ki	=	80	pM	ALA3294545	10.10		nM	Homo sapiens