# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA1231367 | 1 | Ki | = | 110 | nM | ALA4403611 | 6.96 | nM | Escherichia coli | ||
2. | Avibactam | NXL104 | MIC | = | 0.5 | ug ml-1 | ALA4377166 | ug.mL-1 | Escherichia coli | |||
3. | Ceftazidime (containing approximately 10% sodium carbonate) | CAZ | Activity | = | 0.001 | % | ALA1217946 | % | Escherichia coli | |||
4. | Doripenem | Doripenem | Activity | = | 0.002 | % | ALA1217946 | % | Escherichia coli | |||
5. | Meropenem | 3 | Activity | = | 0.001 | % | ALA1217946 | % | Escherichia coli | |||
6. | Imipenem | Imipenem | Activity | = | 0.072 | % | ALA1217946 | % | Escherichia coli | |||
7. | penicillin G | Benzylpenicillin | Activity | = | 5600 | % | ALA1217946 | % | Escherichia coli | |||
8. | Ceftazidime (containing approximately 10% sodium carbonate) | CAZ | Activity | = | 0 | % | ALA1217931 | % | Escherichia coli | |||
9. | Doripenem | Doripenem | Activity | = | 0 | % | ALA1217931 | % | Escherichia coli | |||
10. | Meropenem | 3 | Activity | = | 0 | % | ALA1217931 | % | Escherichia coli | |||
11. | Imipenem | Imipenem | Activity | = | 0.001 | % | ALA1217931 | % | Escherichia coli | |||
12. | penicillin G | Benzylpenicillin | Activity | = | 120 | % | ALA1217931 | % | Escherichia coli | |||
13. | Ceftazidime (containing approximately 10% sodium carbonate) | CAZ | Kcat/Km | = | 0 | /s/microM | ALA1217916 | /s/microM | Escherichia coli | |||
14. | Doripenem | Doripenem | Kcat/Km | = | 0 | /s/microM | ALA1217916 | /s/microM | Escherichia coli | |||
15. | Meropenem | 3 | Kcat/Km | = | 0 | /s/microM | ALA1217916 | /s/microM | Escherichia coli | |||
16. | Imipenem | Imipenem | Kcat/Km | = | 0.001 | /s/microM | ALA1217916 | /s/microM | Escherichia coli | |||
17. | penicillin G | Benzylpenicillin | Kcat/Km | = | 100 | /s/microM | ALA1217916 | /s/microM | Escherichia coli | |||
18. | cefaloridine | cephaloridine | Kcat/Km | = | 1.8 | /s/microM | ALA1217916 | /s/microM | Escherichia coli | |||
19. | Ceftazidime (containing approximately 10% sodium carbonate) | CAZ | Km | = | 200 | uM | ALA1217901 | nM | Escherichia coli | |||
20. | Doripenem | Doripenem | Km | = | 5.4 | uM | ALA1217901 | nM | Escherichia coli |