# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | Selexipag | 31 | IC50 | = | 6.4 | uM | ALA5246771 | 5.19 | nM | Homo sapiens | ||
2. | ALA3286660 | 7z, TG8-15 | Kb | = | 130 | uM | ALA5224045 | nM | Homo sapiens | |||
3. | TG 4-155 | SID17515129 | Kb | = | 62 | uM | ALA5224035 | nM | Homo sapiens | |||
4. | Iloprost | Iloprost | EC50 | = | 0.4 | nM | ALA5127967 | 9.40 | nM | Homo sapiens | ||
5. | Treprostinil | Treprostinil | EC50 | = | 1.9 | nM | ALA5127967 | 8.72 | nM | Homo sapiens | ||
6. | ALA4572891 | 9 | INH | = | 68 | % | ALA4388829 | % | Homo sapiens | |||
7. | Remibrutinib (LOU064) | 25; LOU064 | Activity | 0 | ALA4358655 | Not Active | Homo sapiens | |||||
8. | ALA15245 | yohimbine | INH | = | 8 | % | ALA4344225 | % | Homo sapiens | |||
9. | ALA4451048 | 9 | INH | = | 22 | % | ALA4344225 | % | Homo sapiens | |||
10. | ALA4517604 | 8 | INH | = | 84 | % | ALA4344225 | % | Homo sapiens | |||
11. | ALA4546064 | 6 | INH | = | 22 | % | ALA4344225 | % | Homo sapiens | |||
12. | ALA4558185 | 7; V4a | INH | = | 76 | % | ALA4344225 | % | Homo sapiens | |||
13. | ALA4527708 | 5; V3a | IC50 | = | 12.5 | uM | ALA4344231 | 4.90 | nM | Homo sapiens | ||
14. | ALA4527708 | 5; V3a | INH | = | 97 | % | ALA4344225 | % | Homo sapiens | |||
15. | ALA4592258 | 4; V2a | INH | = | 75 | % | ALA4344225 | % | Homo sapiens | |||
16. | ALA4529035 | 3; V1a | INH | = | 41 | % | ALA4344225 | % | Homo sapiens | |||
17. | Vincamine | vincamine | INH | = | -3 | % | ALA4344225 | % | Homo sapiens | |||
18. | ALA4541923 | 24c; TG11-224 | KB | > | 10 | uM | ALA4325405 | nM | Homo sapiens | |||
19. | ALA4587876 | 24b; TG11-242 | KB | > | 10 | uM | ALA4325405 | nM | Homo sapiens | |||
20. | ALA4537092 | 24a; TG11-228 | KB | > | 10 | uM | ALA4325405 | nM | Homo sapiens |