# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5275789 | 3 | EC50 | = | 1 | nM | ALA5249256 | 9.00 | nM | Homo sapiens | ||
2. | ALA5279134 | 1 | EC50 | = | 13 | nM | ALA5249256 | 7.89 | nM | Homo sapiens | ||
3. | ALA5289415 | 2 | EC50 | = | 680 | nM | ALA5249256 | 6.17 | nM | Homo sapiens | ||
4. | ALA5274468 | 4 | EC50 | = | 3 | nM | ALA5249256 | 8.52 | nM | Homo sapiens | ||
5. | ALA154623 | 12 | IC50 | = | 0.007 | uM | ALA5236690 | 8.15 | nM | Homo sapiens | ||
6. | ALA348270 | 1 | IC50 | = | 0.41 | uM | ALA5236690 | 6.39 | nM | Homo sapiens | ||
7. | ALA133046 | 20 | IC50 | = | 37.5 | nM | ALA5234965 | 7.43 | nM | Homo sapiens | ||
8. | ALA3590047 | 8m | IC50 | = | 1200 | nM | ALA5210222 | 5.92 | nM | Homo sapiens | ||
9. | ALA5193821 | 29 | t1/2 | = | 39 | min | ALA5142001 | hr | Homo sapiens | |||
10. | N-(2-chloro-4-methylpyridin-3-yl)-6-[4-ethyl-3-(hydroxymethyl)-5-oxo-1,2,4-triazol-1-yl]-5-fluoro-2-[(2S)-1,1,1-trifluoropropan-2-yl]oxypyridine-3-carboxamide | 19 | t1/2 | = | 30 | min | ALA5142001 | hr | Homo sapiens | |||
11. | ALA5193821 | 29 | Kd | = | 1.1 | nM | ALA5142000 | 8.96 | nM | Homo sapiens | ||
12. | N-(2-chloro-4-methylpyridin-3-yl)-6-[4-ethyl-3-(hydroxymethyl)-5-oxo-1,2,4-triazol-1-yl]-5-fluoro-2-[(2S)-1,1,1-trifluoropropan-2-yl]oxypyridine-3-carboxamide | 19 | Kd | = | 3.3 | nM | ALA5142000 | 8.48 | nM | Homo sapiens | ||
13. | ALA5206111 | 32 | IC50 | = | 0.8 | nM | ALA5141994 | 9.10 | nM | Homo sapiens | ||
14. | ALA5197655 | 31 | IC50 | = | 11 | nM | ALA5141994 | 7.96 | nM | Homo sapiens | ||
15. | ALA5201357 | 30 | IC50 | = | 10 | nM | ALA5141994 | 8.00 | nM | Homo sapiens | ||
16. | ALA5193821 | 29 | IC50 | = | 0.3 | nM | ALA5141994 | 9.52 | nM | Homo sapiens | ||
17. | ALA5186161 | 28 | IC50 | = | 0.56 | nM | ALA5141994 | 9.25 | nM | Homo sapiens | ||
18. | ALA5209156 | 27 | IC50 | = | 16 | nM | ALA5141994 | 7.80 | nM | Homo sapiens | ||
19. | ALA5209113 | 26 | IC50 | = | 1.1 | nM | ALA5141994 | 8.96 | nM | Homo sapiens | ||
20. | ALA5176109 | 25 | IC50 | = | 2.3 | nM | ALA5141994 | 8.64 | nM | Homo sapiens |