| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  opnurasib | 1a | INH | = | 8 | % | ALA5238527 | % | Homo sapiens | |||
| 2. | opnurasib | 1a | IC50 | > | 10 | uM | ALA5238525 | nM | Homo sapiens | |||
| 3. |  ALA5274306 | 15 | INH | < | 50 | % | ALA5228856 | % | Homo sapiens | |||
| 4. |  BI-1950 | EUB0000310 | % of inhibition | = | 72 | % | ALA5214553 | % | Homo sapiens | |||
| 5. |  ALA5200705 | 26 | INH | = | 19.8 | % | ALA5164181 | % | Homo sapiens | |||
| 6. |  GDC-0077 | INAVOLISIB | INH | < | 20 | % | ALA5153896 | % | Homo sapiens | |||
| 7. |  SAGE-718 | DALZANEMDOR | IC50 | > | 30 | uM | ALA5136760 | nM | Homo sapiens | |||
| 8. |  N-[(2S)-1,1-dicyclopropyl-3-[4-(3,5-dimethyl-1H-pyrazol-4-yl)anilino]-3-oxopropan-2-yl]-2-propan-2-ylpyrazole-3-carboxamide | 23 | INH | 0 | ALA5136713 | NA | % | Homo sapiens | ||||
| 9. |  ALA5198665 | 19 | IC50 | = | 7059 | nM | ALA5133284 | 5.15 | nM | Homo sapiens | ||
| 10. |  ALA5176104 | 25 | IC50 | > | 100 | uM | ALA5131302 | nM | Homo sapiens | |||
| 11. |  ALA5203937 | 19 | IC50 | > | 100 | uM | ALA5129832 | nM | Homo sapiens | |||
| 12. |  4-[[(2R)-2-hydroxy-2-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl]amino]butyl 5-[[3-[(S)-[[(3R)-1-azabicyclo[2.2.2]octan-3-yl]oxycarbonylamino]-phenylmethyl]phenoxy]methyl]-1-methylpyrazole-3-carboxylate | 29 | IC50 | = | 50 | uM | ALA5129832 | 4.30 | nM | Homo sapiens | ||
| 13. |  ALA5201712 | 37b | IC50 | > | 100 | uM | ALA5129832 | nM | Homo sapiens | |||
| 14. |  ALA5204231 | DM131 | IC50 | = | 13.3 | uM | ALA5117278 | 4.88 | nM | Homo sapiens | ||
| 15. |  ALA5180874 | 2; JBD0131 | IC50 | > | 13.3 | uM | ALA5117278 | nM | Homo sapiens | |||
| 16. |  ALA5196079 | WX-081-M3 | IC50 | > | 3 | uM | ALA5116305 | nM | Homo sapiens | |||
| 17. |  ALA5184933 | BDQ-M2 | IC50 | = | 0.75 | uM | ALA5116305 | 6.12 | nM | Homo sapiens | ||
| 18. |  ALA4457557 | 4 | IC50 | > | 33.3 | uM | ALA4431168 | nM | Homo sapiens | |||
| 19. |  MK-7145 | BDBM155921 | IC50 | > | 30 | uM | ALA4427523 | nM | Homo sapiens | |||
| 20. |  ALA4440935 | 29; CYM-51317 | INH | < | 25 | % | ALA4424287 | % | Homo sapiens |
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