| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA3526190 | DB868 | Drug metabolism | 0 | ALA3530778 | metabolite_not_detected | Rattus norvegicus | |||||
| 2. | ALA3526190 | DB868 | Drug metabolism | 0 | ALA3530777 | metabolite_not_detected | Rattus norvegicus | |||||
| 3. |  ALA3527054 | (R)-sulindac | Drug metabolism | 0 | ALA3528180 | metabolite_not_detected | Rattus norvegicus | |||||
| 4. | ALA3527054 | (R)-sulindac | Drug metabolism | 0 | ALA3528174 | metabolite_not_detected | Rattus norvegicus | |||||
| 5. |  Ethinyl Estradiol | 17 alpha-ethynyl E2 | Partition ratio | = | 21 | ALA1743517 | Cytochrome P450 mechanistic inhibitor: PMID 11805216 | Rattus norvegicus | ||||
| 6. |  Thio-TEPA | 2 | Partition ratio | = | 166 | ALA1743516 | Cytochrome P450 mechanistic inhibitor: PMID 15121764 | Rattus norvegicus | ||||
| 7. |  1-(2-Phenylpropan-2-yl)piperidine | 2-phenyl-2-(1-piperidinyl) propane (PPP) | Partition ratio | = | 31 | ALA1743515 | Cytochrome P450 mechanistic inhibitor: PMID 10901699 | Rattus norvegicus | ||||
| 8. |  5-Phenyl-1-pentyne | 5-phenyl pentyne | mechanism based inhibition | 0 | ALA1743494 | Cytochrome P450 mechanistic inhibitor: PMID 9760279 | Rattus norvegicus | |||||
| 9. | Ethinyl Estradiol | 17 alpha-ethynyl E2 | Kinact | = | 0.2 | min-1 | ALA1743493 | Cytochrome P450 mechanistic inhibitor: PMID 11805216 | min-1 | Rattus norvegicus | ||
| 10. | Ethinyl Estradiol | 17 alpha-ethynyl E2 | KI | = | 11 | uM | ALA1743493 | 4.96 | Cytochrome P450 mechanistic inhibitor: PMID 11805216 | nM | Rattus norvegicus | |
| 11. | Thio-TEPA | 2 | Kinact | = | 0.3 | min-1 | ALA1743492 | Cytochrome P450 mechanistic inhibitor: PMID 15121764 | min-1 | Rattus norvegicus | ||
| 12. | Thio-TEPA | 2 | KI | = | 31 | uM | ALA1743492 | 4.51 | Cytochrome P450 mechanistic inhibitor: PMID 15121764 | nM | Rattus norvegicus | |
| 13. |  ALA1794794 | Peroxynitrite | mechanism based inhibition | 0 | ALA1743491 | Cytochrome P450 mechanistic inhibitor: PMID 12588183 | Rattus norvegicus | |||||
| 14. | 1-(2-Phenylpropan-2-yl)piperidine | 2-phenyl-2-(1-piperidinyl) propane (PPP) | Kinact | = | 0.3 | min-1 | ALA1743490 | Cytochrome P450 mechanistic inhibitor: PMID 10901699 | min-1 | Rattus norvegicus | ||
| 15. | 1-(2-Phenylpropan-2-yl)piperidine | 2-phenyl-2-(1-piperidinyl) propane (PPP) | KI | = | 12 | uM | ALA1743490 | 4.92 | Cytochrome P450 mechanistic inhibitor: PMID 10901699 | nM | Rattus norvegicus | |
| 16. |  Bergamottin | 4 | Kinact | = | 0.049 | min-1 | ALA1743489 | Cytochrome P450 mechanistic inhibitor: PMID 15608076 | min-1 | Rattus norvegicus | ||
| 17. | Bergamottin | 4 | KI | = | 2.4 | uM | ALA1743489 | 5.62 | Cytochrome P450 mechanistic inhibitor: PMID 15608076 | nM | Rattus norvegicus | |
| 18. |  4-((4-Hydroxyphenyl)amino)-4-oxobutanoic acid | A | Kd | = | 1.12 | uM | ALA1286936 | 5.95 | nM | Rattus norvegicus | ||
| 19. |  ALA1275863 | B | Kd | = | 24 | uM | ALA1286936 | 4.62 | nM | Rattus norvegicus | ||
| 20. |  Cumene hydroperoxide | SID17389088 | mechanism based inhibition | 0 | ALA1908260 | Cytochrome P450 mechanistic inhibitor: PMID 8416964 | Rattus norvegicus |
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