# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA501778 | 1R, (R)-(+)-higenamine | EC50 | = | 4.5 | uM | ALA4180551 | 5.35 | nM | Rattus norvegicus | ||
2. | ALA470491 | 1S, (S)-(-)-higenamine | EC50 | = | 0.6 | uM | ALA4180551 | 6.22 | nM | Rattus norvegicus | ||
3. | ALA4215907 | 2-(R) | EC50 | = | 9 | uM | ALA4180551 | 5.05 | nM | Rattus norvegicus | ||
4. | ALA3585932 | 1 | EC50 | = | 1.3 | uM | ALA4180551 | 5.89 | nM | Rattus norvegicus | ||
5. | Demethyl-Coclaurine | 3 | FC | > | 2 | ALA4180552 | Rattus norvegicus | |||||
6. | ALA4208096 | 6 | Activity | 0 | ALA4180553 | Active | Rattus norvegicus | |||||
7. | ALA4217848 | 7 | Activity | 0 | ALA4180553 | Active | Rattus norvegicus | |||||
8. | ALA4209013 | 3 | FC | = | 1.2 | ALA4180554 | Rattus norvegicus | |||||
9. | ALA4215209 | 5 | FC | = | 1.2 | ALA4180554 | Rattus norvegicus | |||||
10. | ALA4209013 | 3 | Activity | 0 | ALA4180555 | Active | Rattus norvegicus | |||||
11. | ALA4214986 | 4 | FC | = | 1.6 | ALA4180555 | Rattus norvegicus | |||||
12. | ALA4215209 | 5 | Activity | 0 | ALA4180555 | Active | Rattus norvegicus | |||||
13. | ALA4214986 | 4 | Activity | = | 40 | % | ALA4180556 | % | Rattus norvegicus | |||
14. | L-Adrenaline | 12, (-)-epinephrine | Activity | 0 | ALA4180557 | Active | Rattus norvegicus | |||||
15. | L-Noradrenaline | NE | Activity | 0 | ALA4180557 | Active | Rattus norvegicus | |||||
16. | Demethyl-Coclaurine | 3 | Activity | 0 | ALA4180557 | Active | Rattus norvegicus | |||||
17. | BI-1950 | EUB0000310 | % Ctrl | 84 | % | ALA4887065 | Not Active | % | Rattus norvegicus | |||
18. | BI-1935 | EUB0000542 | % Ctrl | 98 | % | ALA4882496 | Not Active | % | Rattus norvegicus | |||
19. | BI 653048 | (R)-39 | % Ctrl | 75 | % | ALA4882198 | Not Active | % | Rattus norvegicus | |||
20. | ALA3585932 | 1 | Activity | 0 | ALA3588581 | Not Active | Rattus norvegicus |