Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	Remibrutinib (LOU064)	25; LOU064	Activity		0		ALA4358605		Not Active		Rattus norvegicus
2.	ALA558314	1c	EC50	=	5.7	uM	ALA4223233	5.24		nM	Rattus norvegicus
3.	ALA558737	1a	EC50	=	5.4	uM	ALA4223233	5.27		nM	Rattus norvegicus
4.	ALA3958704	8a	INH	<	20	%	ALA4184509			%	Rattus norvegicus
5.	ALA4763515	benzoyl-Vc1.1[N9R]	INH	=	2.2	%	ALA4682108			%	Rattus norvegicus
6.	ALA4795177	21g; VU6005806; AZN-00016130	Activity	>	50	%	ALA4667479			%	Rattus norvegicus
7.	BI 605906	BI605906	% Ctrl		86	%	ALA4887185		Not Active	%	Rattus norvegicus
8.	BI-1950	EUB0000310	% Ctrl		102	%	ALA4887068		Not Active	%	Rattus norvegicus
9.	BI-1935	EUB0000542	% Ctrl		102	%	ALA4882499		Not Active	%	Rattus norvegicus
10.	ALA2170610	60	% Ctrl		98	%	ALA4882326		Not Active	%	Rattus norvegicus
11.	BI 639667	19n	% Ctrl		90	%	ALA4882253		Not Active	%	Rattus norvegicus
12.	BI 653048	(R)-39	% Ctrl		96	%	ALA4882200		Not Active	%	Rattus norvegicus
13.	ALA3417525	69, BI665915	% Ctrl		95	%	ALA4881821		Not Active	%	Rattus norvegicus
14.	ALA3417525	69, BI665915	% Ctrl		96	%	ALA4881708		Not Active	%	Rattus norvegicus
15.	ALA1836968	RgIA	INH	=	60.6	%	ALA3375974			%	Rattus norvegicus
16.	ALA3355196	1	INH		0		ALA3375974		Active	%	Rattus norvegicus
17.	ALA3355197	2, Trans 2,8-dicarba RgIA	INH		0		ALA3375974		Active	%	Rattus norvegicus
18.	ALA3355198	3, Cis 3,12-dicarba RgIA	INH		0		ALA3375975		Not Active	%	Rattus norvegicus
19.	ALA3355199	4, Trans 3,12-dicarba RgIA	INH		0		ALA3375975		Not Active	%	Rattus norvegicus
20.	ALA4064397	16	INH	=	73	%	ALA4028362			%	Rattus norvegicus