# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | Saquinavir | Saquinavir | Ki | = | 1.4 | nM | ALA5247085 | 8.85 | nM | Human immunodeficiency virus 1 | ||
2. | ALA5277648 | 329 | IC50 | = | 0.26 | nM | ALA5247084 | 9.59 | nM | Human immunodeficiency virus 1 | ||
3. | ALA1232930 | 1, GRL-0519 | IC50 | = | 1.8 | nM | ALA5247084 | 8.74 | nM | Human immunodeficiency virus 1 | ||
4. | ALA113090 | 54 | IC50 | = | 17 | nM | ALA5247084 | 7.77 | nM | Human immunodeficiency virus 1 | ||
5. | ALA331599 | 53 | IC50 | = | 190 | nM | ALA5247084 | 6.72 | nM | Human immunodeficiency virus 1 | ||
6. | Saquinavir | Saquinavir | IC50 | = | 0.23 | nM | ALA5247084 | 9.64 | nM | Human immunodeficiency virus 1 | ||
7. | ALA5288702 | 12 | Ki | = | 15.5 | pM | ALA5234388 | 10.81 | nM | Human immunodeficiency virus 1 | ||
8. | ALA5274743 | 11 | Ki | = | 12.9 | pM | ALA5234388 | 10.89 | nM | Human immunodeficiency virus 1 | ||
9. | ALA5282058 | 61 | IC50 | = | 125 | uM | ALA5230250 | nM | Human immunodeficiency virus 1 | |||
10. | ALA414640 | KNI-272 | Ki | = | 0.74 | nM | ALA5229290 | 9.13 | nM | Human immunodeficiency virus 1 | ||
11. | ALA5280289 | 77 | IC50 | = | 2.8 | nM | ALA5229290 | 8.55 | nM | Human immunodeficiency virus 1 | ||
12. | ALA5271231 | 76 | IC50 | = | 8.8 | nM | ALA5229290 | 8.06 | nM | Human immunodeficiency virus 1 | ||
13. | ALA5270344 | 75 | IC50 | = | 31 | nM | ALA5229290 | 7.51 | nM | Human immunodeficiency virus 1 | ||
14. | ALA3349847 | 4 | IC50 | = | 89 | nM | ALA5229290 | 7.05 | nM | Human immunodeficiency virus 1 | ||
15. | ALA300891 | 21f | Ki | = | 0.33 | nM | ALA5229290 | 9.48 | nM | Human immunodeficiency virus 1 | ||
16. | ALA414640 | KNI-272 | IC50 | = | 6.5 | nM | ALA5229290 | 8.19 | nM | Human immunodeficiency virus 1 | ||
17. | ALA4436207 | 177 | Ki | = | 0.5 | pM | ALA5226186 | nM | Human immunodeficiency virus 1 | |||
18. | Darunavir | 13 | Ki | = | 10 | pM | ALA5226186 | 11.00 | nM | Human immunodeficiency virus 1 | ||
19. | ALA5266997 | 3 | Ki | = | 10 | pM | ALA5226184 | 11.00 | nM | Human immunodeficiency virus 1 | ||
20. | ALA5177981 | 8; Enantiomeric mixture | IC50 | = | 77 | uM | ALA5164473 | 4.11 | nM | Human immunodeficiency virus 1 |