# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ceftaroline fosamil | ceftaroline | IC50 | = | 0.049 | ug ml-1 | ALA1667069 | ug.mL-1 | Staphylococcus aureus | |||
2. | ALA1652606 | Ceftobiprole medocaril | IC50 | = | 0.05 | ug ml-1 | ALA1667057 | ug.mL-1 | Staphylococcus aureus | |||
3. | ceftobiprole | BPR, ceftobiprole | Activity | 0 | ALA1278931 | Active | Staphylococcus aureus | |||||
4. | ALA123481 | 3q | IC50 | = | 30 | uM | ALA757153 | 4.52 | nM | Staphylococcus aureus | ||
5. | ALA123481 | 3q | IC50 | > | 300 | uM | ALA758012 | nM | Staphylococcus aureus | |||
6. | ALA333330 | 3m | IC50 | = | 28 | uM | ALA757153 | 4.55 | nM | Staphylococcus aureus | ||
7. | ALA333330 | 3m | IC50 | > | 300 | uM | ALA758012 | nM | Staphylococcus aureus | |||
8. | ALA121924 | 3k | IC50 | = | 145 | uM | ALA757153 | nM | Staphylococcus aureus | |||
9. | ALA121924 | 3k | IC50 | > | 300 | uM | ALA758012 | nM | Staphylococcus aureus | |||
10. | ALA332565 | 3l | IC50 | = | 286 | uM | ALA757153 | nM | Staphylococcus aureus | |||
11. | ALA332565 | 3l | IC50 | = | 286 | uM | ALA758012 | nM | Staphylococcus aureus | |||
12. | ALA6461 | Ro-481220 | IC50 | = | 170 | uM | ALA757154 | nM | Staphylococcus aureus | |||
13. | ALA6461 | Ro-481220 | IC50 | > | 340 | uM | ALA758012 | nM | Staphylococcus aureus | |||
14. | ALA133844 | 5 | Binding affinity | = | 2 | ALA762901 | Staphylococcus aureus | |||||
15. | ALA134016 | 4 | Binding affinity | < | 0.1 | ALA760305 | Staphylococcus aureus | |||||
16. | ALA341086 | 6 | Binding affinity | = | 100 | ALA762901 | Staphylococcus aureus | |||||
17. | ALA341337 | 2 | Binding affinity | = | 2 | ALA762901 | Staphylococcus aureus | |||||
18. | ALA130494 | 26 | Binding affinity | = | 100 | ALA762901 | Staphylococcus aureus | |||||
19. | Cefoperazone | Cefoperazone | Binding affinity | < | 0.1 | ALA762901 | Staphylococcus aureus | |||||
20. | Cefotaxime acid | cefotaxime | Binding affinity | <= | 0.1 | ALA760305 | Staphylococcus aureus |