Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ceftobiprole	BPR, ceftobiprole	Activity		0		ALA1278931		Active		Staphylococcus aureus
2.	ceftaroline fosamil	ceftaroline	IC50	=	0.049	ug ml-1	ALA1667069			ug.mL-1	Staphylococcus aureus
3.	ALA1652606	Ceftobiprole medocaril	IC50	=	0.05	ug ml-1	ALA1667057			ug.mL-1	Staphylococcus aureus
4.	ALA123481	3q	IC50	=	30	uM	ALA757153	4.52		nM	Staphylococcus aureus
5.	ALA123481	3q	IC50	>	300	uM	ALA758012			nM	Staphylococcus aureus
6.	ALA333330	3m	IC50	=	28	uM	ALA757153	4.55		nM	Staphylococcus aureus
7.	ALA333330	3m	IC50	>	300	uM	ALA758012			nM	Staphylococcus aureus
8.	ALA121924	3k	IC50	=	145	uM	ALA757153			nM	Staphylococcus aureus
9.	ALA121924	3k	IC50	>	300	uM	ALA758012			nM	Staphylococcus aureus
10.	ALA332565	3l	IC50	=	286	uM	ALA757153			nM	Staphylococcus aureus
11.	ALA332565	3l	IC50	=	286	uM	ALA758012			nM	Staphylococcus aureus
12.	ALA6461	Ro-481220	IC50	=	170	uM	ALA757154			nM	Staphylococcus aureus
13.	ALA6461	Ro-481220	IC50	>	340	uM	ALA758012			nM	Staphylococcus aureus
14.	ALA133844	5	Binding affinity	=	2		ALA762901				Staphylococcus aureus
15.	ALA134016	4	Binding affinity	<	0.1		ALA760305				Staphylococcus aureus
16.	ALA341086	6	Binding affinity	=	100		ALA762901				Staphylococcus aureus
17.	ALA341337	2	Binding affinity	=	2		ALA762901				Staphylococcus aureus
18.	ALA130494	26	Binding affinity	=	100		ALA762901				Staphylococcus aureus
19.	Cefoperazone	Cefoperazone	Binding affinity	<	0.1		ALA762901				Staphylococcus aureus
20.	Cefotaxime acid	cefotaxime	Binding affinity	<=	0.1		ALA760305				Staphylococcus aureus