# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | 4-Ethyl-N-(4-(1-(tetrahydro-2H-pyran-4-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl)pyridin-2-yl)piperazine-1-carboxamide | 13g; GNF2133 | INH | = | 90 | % | ALA5235859 | % | Homo sapiens | |||
2. | ALA5267954 | 17 | INH | 0 | ALA5224707 | Active | % | Homo sapiens | ||||
3. | ALA5286856 | 28 | Kd | = | 10 | nM | ALA5224687 | 8.00 | nM | Homo sapiens | ||
4. | ALA5277132 | 27 | Kd | = | 325 | nM | ALA5224687 | 6.49 | nM | Homo sapiens | ||
5. | ALA5288822 | 26 | Kd | = | 1200 | nM | ALA5224687 | 5.92 | nM | Homo sapiens | ||
6. | ALA5286467 | 25 | Kd | = | 10 | nM | ALA5224687 | 8.00 | nM | Homo sapiens | ||
7. | ALA5277405 | 24 | Kd | = | 10 | nM | ALA5224687 | 8.00 | nM | Homo sapiens | ||
8. | ALA5277359 | 23 | Kd | = | 14 | nM | ALA5224687 | 7.85 | nM | Homo sapiens | ||
9. | ALA5288133 | 22 | Kd | = | 70 | nM | ALA5224687 | 7.16 | nM | Homo sapiens | ||
10. | GSK2983559 (compound 3) | 5; GSK2983559 | Kd | = | 0.78 | nM | ALA5224687 | 9.11 | nM | Homo sapiens | ||
11. | ALA5279827 | 21 | Kd | = | 545 | nM | ALA5224687 | 6.26 | nM | Homo sapiens | ||
12. | ALA5286275 | 20 | Kd | = | 109 | nM | ALA5224687 | 6.96 | nM | Homo sapiens | ||
13. | ALA5279908 | 19 | Kd | = | 3.3 | nM | ALA5224687 | 8.48 | nM | Homo sapiens | ||
14. | ALA5271765 | 18 | Kd | = | 27 | nM | ALA5224687 | 7.57 | nM | Homo sapiens | ||
15. | ALA5267954 | 17 | Kd | = | 5.9 | nM | ALA5224687 | 8.23 | nM | Homo sapiens | ||
16. | ALA5274710 | 16 | Kd | = | 14 | nM | ALA5224687 | 7.85 | nM | Homo sapiens | ||
17. | ALA5287768 | 15 | Kd | = | 24 | nM | ALA5224687 | 7.62 | nM | Homo sapiens | ||
18. | ALA5274652 | 14 | Kd | = | 8.2 | nM | ALA5224687 | 8.09 | nM | Homo sapiens | ||
19. | ALA5290584 | 13 | Kd | = | 685 | nM | ALA5224687 | 6.16 | nM | Homo sapiens | ||
20. | ALA5276428 | 12 | Kd | = | 55 | nM | ALA5224687 | 7.26 | nM | Homo sapiens |