Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA4554361	14	IC50	>	50	uM	ALA4427251			nM	Homo sapiens
2.	ALA4098822	1	IC50	>	40	uM	ALA4427251			nM	Homo sapiens
3.	ALA179544	18	Ki	=	9.7	uM	ALA4422431	5.01		nM	Homo sapiens
4.	3-(2-methyl-1H-imidazol-1-yl)pyridine	62	INH		0		ALA4422409		Active	%	Homo sapiens
5.	ALA180270	51	INH		0		ALA4422406		Tde	%	Homo sapiens
6.	ALA149808	5	INH		0		ALA4422406		Tde	%	Homo sapiens
7.	3-(Pyridin-3-yl)prop-2-yn-1-amine	48	INH		0		ALA4422406		Tde	%	Homo sapiens
8.	ALA180270	51	Ki	=	0.04	uM	ALA4422408	7.40		nM	Homo sapiens
9.	ALA149808	5	Ki	=	0.04	uM	ALA4422408	7.40		nM	Homo sapiens
10.	3-(1H-Imidazol-5-yl)pyridine	34	Ki	=	9.8	uM	ALA4422408	5.01		nM	Homo sapiens
11.	3-(Pyridin-3-yl)prop-2-yn-1-amine	48	Ki	=	0.04	uM	ALA4422408	7.40		nM	Homo sapiens
12.	ALA180270	51	Kinact	=	0.02	/min	ALA4422407			/min	Homo sapiens
13.	ALA149808	5	Kinact	=	0.02	/min	ALA4422407			/min	Homo sapiens
14.	3-(1H-Imidazol-5-yl)pyridine	34	Kinact	=	0.04	/min	ALA4422407			/min	Homo sapiens
15.	3-(Pyridin-3-yl)prop-2-yn-1-amine	48	Kinact	=	0.02	/min	ALA4422407			/min	Homo sapiens
16.	ALA4483324	Table 9, R34C1	IC50	=	4.67	uM	ALA4422401	5.33		nM	Homo sapiens
17.	ALA4583840	Table 9, R28C1	IC50	=	2.41	uM	ALA4422401	5.62		nM	Homo sapiens
18.	ALA4564967	Table 9, R24C1	IC50	=	1.82	uM	ALA4422401	5.74		nM	Homo sapiens
19.	ALA4584362	Table 9, R22C1	IC50	<=	1.68	uM	ALA4422401			nM	Homo sapiens
20.	ALA4466954	Table 12-13, cpd 37a,b	IC50	=	9.8	uM	ALA4422401	5.01		nM	Homo sapiens