# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3086863 | 7h | INH | 0 | ALA3088997 | Not Active | % | Homo sapiens | ||||
2. | ALA3086864 | 3a | INH | 0 | ALA3088997 | Active | % | Homo sapiens | ||||
3. | ALA3086865 | 3b | INH | 0 | ALA3088997 | Active | % | Homo sapiens | ||||
4. | ALA3086866 | 3c | INH | 0 | ALA3088997 | Active | % | Homo sapiens | ||||
5. | ALA3086867 | 3d | INH | 0 | ALA3088997 | Active | % | Homo sapiens | ||||
6. | Folic acid | Folic acid | INH | 0 | ALA3088997 | Active | % | Homo sapiens | ||||
7. | ALA1834488 | 3 | IC50 | = | 0.17 | nM | ALA3387473 | 9.77 | nM | Homo sapiens | ||
8. | ALA3335603 | 9 | IC50 | > | 1000 | nM | ALA3387473 | nM | Homo sapiens | |||
9. | ALA3335604 | 10 | IC50 | = | 347 | nM | ALA3387473 | 6.46 | nM | Homo sapiens | ||
10. | ALA3335605 | 11 | IC50 | = | 3.6 | nM | ALA3387473 | 8.44 | nM | Homo sapiens | ||
11. | ALA3335606 | 12 | IC50 | > | 1000 | nM | ALA3387473 | nM | Homo sapiens | |||
12. | ALA3335607 | 13 | IC50 | > | 1000 | nM | ALA3387473 | nM | Homo sapiens | |||
13. | [³H]methotrexate | 138 | IC50 | = | 106 | nM | ALA3387473 | 6.97 | nM | Homo sapiens | ||
14. | Pemetrexed | 2 (LY-231514) | IC50 | = | 60 | nM | ALA3387473 | 7.22 | nM | Homo sapiens | ||
15. | Raltitrexed | 8a | IC50 | = | 22 | nM | ALA3387473 | 7.66 | nM | Homo sapiens | ||
16. | ALA1834488 | 3 | IC50 | > | 1000 | nM | ALA3387474 | nM | Homo sapiens | |||
17. | ALA3335603 | 9 | IC50 | > | 1000 | nM | ALA3387474 | nM | Homo sapiens | |||
18. | ALA3335604 | 10 | IC50 | > | 1000 | nM | ALA3387474 | nM | Homo sapiens | |||
19. | ALA3335605 | 11 | IC50 | > | 1000 | nM | ALA3387474 | nM | Homo sapiens | |||
20. | ALA3335606 | 12 | IC50 | > | 1000 | nM | ALA3387474 | nM | Homo sapiens |