# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | Glabridin | Glabridin | kinact | = | 0.08 | min-1 | ALA1908242 | Cytochrome P450 mechanistic inhibitor: PMID 12019199 | min-1 | Homo sapiens | ||
2. | GNE-0877 | 11, GNE-0877 | Activity | 0 | ALA3124044 | Active | Homo sapiens | |||||
3. | GNE-9605 | 20, GNE-9605 | Activity | 0 | ALA3124044 | Not Active | Homo sapiens | |||||
4. | 2-PHENYLCYCLOPROPAN-1-AMINE | SID90340789 | IC50 | = | 6900 | nM | ALA3887127 | 5.16 | 312112 | nM | Homo sapiens | |
5. | ALA567597 | 1 | INH | < | 10 | % | ALA3528886 | % | Homo sapiens | |||
6. | ALA567597 | 1 | FC | = | 3.1 | ALA3528889 | Homo sapiens | |||||
7. | ALA252518 | 2 | FC | = | 2.9 | ALA3528889 | Homo sapiens | |||||
8. | Rifampicin | rifampacin | FC | = | 13.9 | ALA3528889 | Homo sapiens | |||||
9. | ALA567597 | 1 | Activity | 0 | ALA3536696 | Dose-dependent effect | Homo sapiens | |||||
10. | ALA567597 | 1 | Activity | = | 18 | % | ALA3528889 | % | Homo sapiens | |||
11. | ALA252518 | 2 | Activity | = | 11.3 | % | ALA3528889 | % | Homo sapiens | |||
12. | ALA567597 | 1 | Emax | = | 1.9 | ALA3528889 | Homo sapiens | |||||
13. | ALA3542332 | M28 | Compound recovery | = | 0.9 | % | ALA3541892 | % | Homo sapiens | |||
14. | ALA3542331 | M15 | Compound recovery | = | 2.06 | % | ALA3541892 | % | Homo sapiens | |||
15. | Boceprevir Metabolite M4 | M4 | Compound recovery | = | 0.22 | % | ALA3541892 | % | Homo sapiens | |||
16. | ALA1233448 | SCH 534128 | Compound recovery | = | 56.54 | % | ALA3541892 | % | Homo sapiens | |||
17. | Tamoxifen | Tamoxifen | Drug metabolism | 0 | ALA3541599 | metabolite_detected | Homo sapiens | |||||
18. | ALA3526434 | 4-OHtam quinone methide | Retention_time | = | 18.3 | min | ALA3541598 | min | Homo sapiens | |||
19. | ALA2137046 | 2 | Retention_time | = | 2 | min | ALA3541600 | min | Homo sapiens | |||
20. | ALA3526434 | 4-OHtam quinone methide | Retention_time | = | 16.9 | min | ALA3541601 | min | Homo sapiens |