# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | sitagliptin | Sitagliptin | IC50 | = | 14.7 | nM | ALA4338413 | 7.83 | nM | Mus musculus | ||
2. | ALA4584732 | 12 | IC50 | = | 168.1 | nM | ALA4338413 | 6.77 | nM | Mus musculus | ||
3. | ALA4532312 | 11 | IC50 | = | 3.5 | nM | ALA4338413 | 8.46 | nM | Mus musculus | ||
4. | ALA4533178 | 10 | IC50 | = | 2.2 | nM | ALA4338413 | 8.66 | nM | Mus musculus | ||
5. | ALA4445546 | 9 | IC50 | = | 81.8 | nM | ALA4338413 | 7.09 | nM | Mus musculus | ||
6. | ALA4452661 | 8 | IC50 | = | 2 | nM | ALA4338413 | 8.70 | nM | Mus musculus | ||
7. | ALA4463027 | 7 | IC50 | = | 1.1 | nM | ALA4338413 | 8.96 | nM | Mus musculus | ||
8. | ALA4442618 | 6 | IC50 | = | 115.7 | nM | ALA4338413 | 6.94 | nM | Mus musculus | ||
9. | ALA4443285 | 5 | IC50 | = | 3 | nM | ALA4338413 | 8.52 | nM | Mus musculus | ||
10. | ALA4593371 | 4 | IC50 | = | 1.4 | nM | ALA4338413 | 8.85 | nM | Mus musculus | ||
11. | Cofrogliptin | 2; Haisco HSK7653 | INH | 0 | ALA4616392 | Dose-dependent effect | % | Mus musculus | ||||
12. | Omarigliptin (MK-3102) | OMARIGLIPTIN | INH | 0 | ALA4616393 | Active | % | Mus musculus | ||||
13. | Omarigliptin (MK-3102) | OMARIGLIPTIN | Time | = | 18 | hr | ALA4616394 | hr | Mus musculus | |||
14. | Cofrogliptin | 2; Haisco HSK7653 | Time | = | 72 | hr | ALA4616394 | hr | Mus musculus | |||
15. | Cofrogliptin | 2; Haisco HSK7653 | Ratio | = | 4 | ALA4616395 | Mus musculus | |||||
16. | Omarigliptin (MK-3102) | OMARIGLIPTIN | IC50 | = | 43.9 | nM | ALA3239619 | 7.36 | nM | Mus musculus | ||
17. | ALA4090635 | 6d | IC50 | = | 7170 | nM | ALA4021429 | 5.14 | nM | Mus musculus | ||
18. | ALA4078112 | 6c | IC50 | = | 2470 | nM | ALA4021429 | 5.61 | nM | Mus musculus | ||
19. | ALA4086264 | 6b | IC50 | = | 488 | nM | ALA4021429 | 6.31 | nM | Mus musculus | ||
20. | ALA4067185 | 6a | IC50 | = | 217 | nM | ALA4021429 | 6.66 | nM | Mus musculus |