# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4463882 | 22d | IC50 | = | 74.3 | uM | ALA4403242 | 4.13 | nM | Homo sapiens | ||
2. | ALA4574361 | 22c | IC50 | > | 100 | uM | ALA4403242 | nM | Homo sapiens | |||
3. | ALA4550042 | 22b | IC50 | > | 100 | uM | ALA4403242 | nM | Homo sapiens | |||
4. | ALA4460845 | 21e | IC50 | = | 36.3 | uM | ALA4403242 | 4.44 | nM | Homo sapiens | ||
5. | [5-[3-ethyl-5-(1-methylpyrazol-4-yl)phenyl]sulfonyl-1,3-thiazol-2-yl]methanamine | 21b | IC50 | = | 19.6 | uM | ALA4403242 | 4.71 | nM | Homo sapiens | ||
6. | ALA4457897 | 21a | IC50 | = | 13.3 | uM | ALA4403242 | 4.88 | nM | Homo sapiens | ||
7. | ALA4515085 | 18 | IC50 | = | 1.3 | uM | ALA4403242 | 5.89 | nM | Homo sapiens | ||
8. | ALA4564074 | 7e | IC50 | = | 3.6 | uM | ALA4403242 | 5.44 | nM | Homo sapiens | ||
9. | ALA4568508 | 7a | IC50 | = | 1.2 | uM | ALA4403242 | 5.92 | nM | Homo sapiens | ||
10. | ALA4457629 | 6 | IC50 | = | 47.1 | uM | ALA4403242 | 4.33 | nM | Homo sapiens | ||
11. | ALA4439437 | 5 | pIC50 | < | 5.5 | ALA4323282 | nM | Homo sapiens | ||||
12. | ALA4562149 | 4 | pIC50 | = | 7.3 | ALA4323282 | 7.30 | nM | Homo sapiens | |||
13. | ALA4472333 | 12b | pIC50 | = | 5.1 | ALA4323282 | 5.10 | nM | Homo sapiens | |||
14. | ALA4531065 | 10h | pIC50 | < | 4.5 | ALA4323282 | nM | Homo sapiens | ||||
15. | Benzylamine | 21 | Drug metabolism | = | 101.9 | % | ALA4323321 | % | Homo sapiens | |||
16. | ALA4569453 | 10g | pIC50 | < | 4.5 | ALA4323282 | nM | Homo sapiens | ||||
17. | ALA4457578 | 12k; PXS-5120A | IC50 | > | 30000 | nM | ALA4323282 | nM | Homo sapiens | |||
18. | ALA4581458 | 3; PXS-5153A | FC | = | 1.6 | ALA4323271 | Homo sapiens | |||||
19. | ALA4451632 | 12o; PXS-5129A | FC | = | 2.4 | ALA4323271 | Homo sapiens | |||||
20. | ALA4586209 | 12n; des-fluoro PXS-5120A | FC | = | 1 | ALA4323271 | Homo sapiens |