# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA441158 | 1 (Sandramycin) | IC50 | = | 0.13 | nM | ALA5241460 | 9.89 | nM | Human immunodeficiency virus 1 | ||
2. | ALA5281264 | 36b | IC50 | = | 0.03 | uM | ALA5238638 | 7.52 | nM | Human immunodeficiency virus 1 | ||
3. | ALA5282652 | 36a | IC50 | = | 0.05 | uM | ALA5238638 | 7.30 | nM | Human immunodeficiency virus 1 | ||
4. | ALA5281060 | 21c | IC50 | = | 0.04 | uM | ALA5238638 | 7.40 | nM | Human immunodeficiency virus 1 | ||
5. | 4-((6-Amino-5-bromo-2-((4-cyanophenyl)amino)pyrimidin-4-yl)oxy)-3,5-dimethylbenzonitrile | 25 | IC50 | = | 0.01 | uM | ALA5238638 | 8.00 | nM | Human immunodeficiency virus 1 | ||
6. | ALA5281981 | 36c | IC50 | = | 0.04 | uM | ALA5238638 | 7.40 | nM | Human immunodeficiency virus 1 | ||
7. | ALA5282652 | 36a | Kd | = | 2.5 | uM | ALA5238637 | 5.60 | nM | Human immunodeficiency virus 1 | ||
8. | 4-((6-Amino-5-bromo-2-((4-cyanophenyl)amino)pyrimidin-4-yl)oxy)-3,5-dimethylbenzonitrile | 25 | Kd | = | 1.46 | uM | ALA5238637 | 5.84 | nM | Human immunodeficiency virus 1 | ||
9. | 10Z-Hymenialdisine | 1 (Hymenialdisine) | INH | = | 90 | % | ALA5227453 | % | Human immunodeficiency virus 1 | |||
10. | ALA204900 | 9 | IC50 | = | 2.5 | uM | ALA5163706 | 5.60 | nM | Human immunodeficiency virus 1 | ||
11. | Nevirapine | nevirapine | INH | = | 84.91 | % | ALA5157624 | % | Human immunodeficiency virus 1 | |||
12. | ALA5194261 | 4e | INH | = | 5.44 | % | ALA5157621 | % | Human immunodeficiency virus 1 | |||
13. | 4-((6-Amino-5-bromo-2-((4-cyanophenyl)amino)pyrimidin-4-yl)oxy)-3,5-dimethylbenzonitrile | 25 | IC50 | = | 694.8 | nM | ALA5144840 | 6.16 | nM | Human immunodeficiency virus 1 | ||
14. | ALA5174976 | 22 | IC50 | = | 119.1 | nM | ALA5144840 | 6.92 | nM | Human immunodeficiency virus 1 | ||
15. | ALA5177915 | 20 | IC50 | = | 123.5 | nM | ALA5144840 | 6.91 | nM | Human immunodeficiency virus 1 | ||
16. | ALA85059 | 80 | IC50 | = | 4.8 | nM | ALA5144840 | 8.32 | nM | Human immunodeficiency virus 1 | ||
17. | Efavirenz | Efavirenz | IC50 | = | 0.011 | uM | ALA5140369 | 7.96 | nM | Human immunodeficiency virus 1 | ||
18. | Nevirapine | nevirapine | IC50 | = | 0.705 | uM | ALA5140369 | 6.15 | nM | Human immunodeficiency virus 1 | ||
19. | ALA5188648 | B39 | IC50 | = | 203.36 | uM | ALA5140369 | nM | Human immunodeficiency virus 1 | |||
20. | ALA5175287 | B38 | IC50 | = | 13.078 | uM | ALA5140369 | 4.88 | nM | Human immunodeficiency virus 1 |