# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | Lovastatin | Mevinolin | IC50 | = | 29.5 | nM | ALA2351479 | 7.53 | nM | Homo sapiens | ||
2. | Atorvastatin | Atorvastatin | IC50 | = | 12.9 | nM | ALA2351479 | 7.89 | nM | Homo sapiens | ||
3. | Vorinostat (SAHA, MK0683) | SAHA | IC50 | > | 10000 | nM | ALA2351479 | nM | Homo sapiens | |||
4. | ALA2347010 | 6a | IC50 | = | 36.5 | nM | ALA2351479 | 7.44 | nM | Homo sapiens | ||
5. | ALA2347011 | 6b | IC50 | = | 53.8 | nM | ALA2351479 | 7.27 | nM | Homo sapiens | ||
6. | ALA2347005 | 10 | IC50 | = | 54.1 | nM | ALA2351479 | 7.27 | nM | Homo sapiens | ||
7. | ALA2347006 | 12, lova-HA | IC50 | = | 16.8 | nM | ALA2351479 | 7.78 | nM | Homo sapiens | ||
8. | ALA2347007 | 13, simva-HA | IC50 | = | 13.1 | nM | ALA2351479 | 7.88 | nM | Homo sapiens | ||
9. | ALA2347008 | 14, atorva-HA | IC50 | = | 12.3 | nM | ALA2351479 | 7.91 | nM | Homo sapiens | ||
10. | ALA2347009 | 15, rosuva-HA | IC50 | = | 43.7 | nM | ALA2351479 | 7.36 | nM | Homo sapiens | ||
11. | Lovastatin | Mevinolin | IC50 | = | 19.8 | uM | ALA2351234 | 4.70 | nM | Homo sapiens | ||
12. | Vorinostat (SAHA, MK0683) | SAHA | IC50 | 0 | ALA2351234 | ND(toxic) | Homo sapiens | |||||
13. | ALA2347010 | 6a | IC50 | = | 22.3 | uM | ALA2351234 | 4.65 | nM | Homo sapiens | ||
14. | ALA2347011 | 6b | IC50 | = | 16.1 | uM | ALA2351234 | 4.79 | nM | Homo sapiens | ||
15. | ALA2347005 | 10 | IC50 | = | 13.2 | uM | ALA2351234 | 4.88 | nM | Homo sapiens | ||
16. | ALA2347006 | 12, lova-HA | IC50 | = | 15.9 | uM | ALA2351234 | 4.80 | nM | Homo sapiens | ||
17. | ALA2347007 | 13, simva-HA | IC50 | = | 7.9 | uM | ALA2351234 | 5.10 | nM | Homo sapiens | ||
18. | ALA2347008 | 14, atorva-HA | IC50 | = | 5.7 | uM | ALA2351234 | 5.24 | nM | Homo sapiens | ||
19. | ALA2347009 | 15, rosuva-HA | IC50 | = | 14.9 | uM | ALA2351234 | 4.83 | nM | Homo sapiens | ||
20. | ALA2347010 | 6a | INH | 0 | ALA2351234 | Dose-dependent effect | % | Homo sapiens |