# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5272983 | 29 | IC50 | = | 2 | uM | ALA5246774 | 5.70 | nM | Homo sapiens | ||
2. | ALA4761843 | EUB0000348aPTSA | Ki | = | 13000 | nM | ALA5214399 | 4.89 | nM | Homo sapiens | ||
3. | ALA4761843 | EUB0000348aPTSA | % of inhibition | = | 56 | % | ALA5214398 | % | Homo sapiens | |||
4. | A192621 | 38 | IC50 | = | 4.5 | nM | ALA5210566 | 8.35 | nM | Homo sapiens | ||
5. | A192621 | 38 | IC50 | = | 0.8 | nM | ALA5210272 | 9.10 | nM | Homo sapiens | ||
6. | ALA4533479 | EUB0000339 | IC50 | > | 10000 | nM | ALA5210266 | nM | Homo sapiens | |||
7. | A192621 | 38 | EC50 | > | 10000 | nM | ALA5210078 | nM | Homo sapiens | |||
8. | IRL-2500 | 13 | IC50 | = | 1.3 | nM | ALA4431780 | 8.89 | nM | Homo sapiens | ||
9. | Feloprentan | (S)-11h | Ki | = | 4.75 | nM | ALA4431784 | 8.32 | nM | Homo sapiens | ||
10. | ALA4568795 | 19; BQ788 | IC50 | = | 1.2 | nM | ALA4431777 | 8.92 | nM | Homo sapiens | ||
11. | ALA112624 | 6b | IC50 | = | 12 | nM | ALA4431774 | 7.92 | nM | Homo sapiens | ||
12. | Bosentan | Bosentan | IC50 | = | 202 | nM | ALA4431774 | 6.70 | nM | Homo sapiens | ||
13. | ALA4559129 | 91 | Ki | = | 25 | nM | ALA4426324 | 7.60 | nM | Homo sapiens | ||
14. | Macitentan | MACITENTAN | IC50 | = | 987 | nM | ALA4426320 | 6.01 | nM | Homo sapiens | ||
15. | ALA4435789 | 93 | IC50 | = | 3.5 | nM | ALA4426324 | 8.46 | nM | Homo sapiens | ||
16. | Zibotentan (ZD4054) | ZIBOTENTAN | IC50 | > | 100 | nM | ALA4426324 | nM | Homo sapiens | |||
17. | ALA330425 | rac-9b | IC50 | = | 184 | nM | ALA4426324 | 6.74 | nM | Homo sapiens | ||
18. | Ambrisentan | rac-2 | IC50 | = | 195 | nM | ALA4426324 | 6.71 | nM | Homo sapiens | ||
19. | Lu-135252 | 1, (LU-135252) | Ki | = | 371 | nM | ALA4426324 | 6.43 | nM | Homo sapiens | ||
20. | ALA293012 | 79 | IC50 | = | 1.8 | uM | ALA4426324 | 5.75 | nM | Homo sapiens |