# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2442940 | 10d | INH | 0 | ALA2446815 | Not Active | % | Homo sapiens | ||||
2. | GR 203040 | 1, GR-203040 | IC50 | = | 0.04 | nM | ALA2447076 | 10.40 | nM | Homo sapiens | ||
3. | ALA2441368 | 6, CP99994 | IC50 | = | 0.17 | nM | ALA2447076 | 9.77 | nM | Homo sapiens | ||
4. | ALA425956 | 9c | IC50 | = | 0.09 | nM | ALA2447076 | 10.05 | nM | Homo sapiens | ||
5. | Aprepitant | 2 | IC50 | = | 0.09 | nM | ALA2447076 | 10.05 | nM | Homo sapiens | ||
6. | ALA22194 | 1a | IC50 | = | 0.2 | nM | ALA2447076 | 9.70 | nM | Homo sapiens | ||
7. | vestipitant | 14aa | IC50 | = | 0.25 | nM | ALA2447076 | 9.60 | nM | Homo sapiens | ||
8. | ALA2441369 | 7, CP211754 | IC50 | = | 0.61 | nM | ALA2447076 | 9.21 | nM | Homo sapiens | ||
9. | ALA16192 | CP-96345 | IC50 | = | 0.66 | nM | ALA2447076 | 9.18 | nM | Homo sapiens | ||
10. | Netupitant | 21, Netupitant | IC50 | = | 0.95 | nM | ALA2447076 | 9.02 | nM | Homo sapiens | ||
11. | ALA27006 | 2 | IC50 | = | 1 | nM | ALA2447076 | 9.00 | nM | Homo sapiens | ||
12. | ALA2441372 | 3b | pKi | = | 9.7 | ALA2447345 | 9.70 | nM | Homo sapiens | |||
13. | ALA2441371 | 3d | pKi | = | 9.86 | ALA2447345 | 9.86 | nM | Homo sapiens | |||
14. | ALA2441373 | 3c | pKi | = | 10.19 | ALA2447345 | 10.19 | nM | Homo sapiens | |||
15. | Orvepitant | ORVEPITANT | pKi | = | 10.2 | ALA2447345 | 10.20 | nM | Homo sapiens | |||
16. | Orvepitant | ORVEPITANT | pKb | = | 10.3 | ALA2447344 | Homo sapiens | |||||
17. | ALA2441373 | 3c | pKb | = | 10.5 | ALA2447344 | Homo sapiens | |||||
18. | ALA2441372 | 3b | pKb | 0 | ALA2447344 | Not Determined | Homo sapiens | |||||
19. | ALA2441371 | 3d | pKb | 0 | ALA2447344 | Not Determined | Homo sapiens | |||||
20. | VU 0409106 | 24, VU0409106 | INH | > | 35 | % | ALA2445484 | % | Homo sapiens |