Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA5283294	48	IC50	<	0.488	nM	ALA5237505			nM	Homo sapiens
2.	Roflumilast	table 2 Roflumilast (17)	IC50	=	0.7	nM	ALA5236724	9.15		nM	Homo sapiens
3.	ALA511115	1 (Ariflo)	IC50	=	398	nM	ALA5236724	6.40		nM	Homo sapiens
4.	ALA2172374	2d	IC50	=	123	nM	ALA5236724	6.91		nM	Homo sapiens
5.	4-[8-(2,1,3-Benzoxadiazol-5-yl)-1,7-naphthyridin-6-yl]benzoic acid	1	IC50	=	602	nM	ALA5236724	6.22		nM	Homo sapiens
6.	N,N,2-Trimethyl-5-nitrobenzenesulfonamide	BRL-50481	IC50	=	62	uM	ALA5227544	4.21		nM	Homo sapiens
7.	ALA5288859	167; BC8-15	IC50	=	0.22	uM	ALA5226661	6.66		nM	Homo sapiens
8.	ALA4518342	EUB0000744	Ki	=	9.83	uM	ALA5213977	5.01		nM	Homo sapiens
9.	THPP-1	THPP-1	Ki	=	5900	nM	ALA5214029	5.23		nM	Homo sapiens
10.	GLPG1205	122	INH		0		ALA5159699		NA	%	Homo sapiens
11.	ALA5179395	33	INH		0		ALA5159699		NA	%	Homo sapiens
12.	Pentoxifylline	Pentoxifylline	IC50	=	168	uM	ALA4425308			nM	Homo sapiens
13.	ALA1229585	SID11113488	IC50	=	4.3	uM	ALA4425308	5.37		nM	Homo sapiens
14.	4-[8-(3-nitrophenyl)-1,7-naphthyridin-6-yl]benzoic Acid	2	IC50	=	3.3	uM	ALA4425309	5.48		nM	Homo sapiens
15.	BPN14770	ZATOLMILAST	INH		0		ALA4397285		Not Active	%	Homo sapiens
16.	BPN14770	ZATOLMILAST	INH		0		ALA4397283		Not Active	%	Homo sapiens
17.	Apremilast	1S	INH	=	91	%	ALA4395209			%	Homo sapiens
18.	Apremilast	1S	INH	=	57	%	ALA4395186			%	Homo sapiens
19.	Apremilast	1S	INH	=	8	%	ALA4395164			%	Homo sapiens
20.	ALA4468513	3b; DRILS-1765	INH	=	36	%	ALA4395106			%	Homo sapiens