Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Assay	Assay Organism
1.	Zanubrutinib (BGB-3111)	BDBM250082	IC50	=	379	nM	ALA5213087	6.42	nM	Homo sapiens
2.	Lorlatinib	8k, PF-06463922	Ki	=	53	nM	ALA5213173	7.28	nM	Homo sapiens
3.	LDC1267	7; LDC1267	% of control	<	10	%	ALA5212940		%	Homo sapiens
4.	BMS-777607	10, BMS-777607	% of control	=	0.55	%	ALA5212882		%	Homo sapiens
5.	Dasatinib	2, BMS-354825	Kd	=	0.31	nM	ALA4419202	9.51	nM	Homo sapiens
6.	Motesanib	AMG-706	Kd	=	99	nM	ALA4419202	7.00	nM	Homo sapiens
7.	Doramapimod	45	Kd	=	360	nM	ALA4419202	6.44	nM	Homo sapiens
8.	Pelitinib	EKB-569	Kd	=	190	nM	ALA4419202	6.72	nM	Homo sapiens
9.	MnTMPyP pentachloride	5	Kd	=	440	nM	ALA4419202	6.36	nM	Homo sapiens
10.	Vandetanib	22	Kd	=	480	nM	ALA4419202	6.32	nM	Homo sapiens
11.	Ibrutinib (PCI-32765)	SID124898784	IC50	=	79	nM	ALA4414922	7.10	nM	Homo sapiens
12.	Zanubrutinib (BGB-3111)	BDBM250082	IC50	=	379	nM	ALA4414922	6.42	nM	Homo sapiens
13.	ALA4445335	Roxyl-ZV-5J	INH	=	10	%	ALA4408109		%	Homo sapiens
14.	ALA4455923	48c	INH	<	50	%	ALA4405383		%	Homo sapiens
15.	ALA4559936	(+/-)-6	Activity	=	99	%	ALA4391358		%	Homo sapiens
16.	ALA4564973	50	INH	=	99	%	ALA4389732		%	Homo sapiens
17.	ALA4555459	43	INH	=	96	%	ALA4389255		%	Homo sapiens
18.	ALA4545456	24	INH	=	1.5	%	ALA4387249		%	Homo sapiens
19.	Abemaciclib	ABEMACICLIB	INH	=	5.5	%	ALA4387249		%	Homo sapiens
20.	ALA4473365	7c	Activity	=	5.9	%	ALA4382536		%	Homo sapiens