Activities

#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay	Assay Organism
1.	6-Fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-1，4-dihydro-[1，3]thiazeto[3，2-a]quinoline-3-carboxylic acid	29a	INH	=	16	%	ALA1641081	%	Aeromonas sp.
2.	6-Fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-1，4-dihydro-[1，3]thiazeto[3，2-a]quinoline-3-carboxylic acid	29a	INH	=	55	%	ALA1641082	%	Aeromonas sp.
3.	6-Fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-1，4-dihydro-[1，3]thiazeto[3，2-a]quinoline-3-carboxylic acid	29a	INH	=	68	%	ALA1641083	%	Aeromonas sp.
4.	6-Fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-1，4-dihydro-[1，3]thiazeto[3，2-a]quinoline-3-carboxylic acid	29a	INH	=	78	%	ALA1641084	%	Aeromonas sp.
5.	6-Fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-1，4-dihydro-[1，3]thiazeto[3，2-a]quinoline-3-carboxylic acid	29a	INH	=	87	%	ALA1641085	%	Aeromonas sp.
6.	6-Fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-1，4-dihydro-[1，3]thiazeto[3，2-a]quinoline-3-carboxylic acid	29a	INH	=	92	%	ALA1641241	%	Aeromonas sp.
7.	6-Fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-1，4-dihydro-[1，3]thiazeto[3，2-a]quinoline-3-carboxylic acid	29a	INH	=	93	%	ALA1641242	%	Aeromonas sp.
8.	6-Fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-1，4-dihydro-[1，3]thiazeto[3，2-a]quinoline-3-carboxylic acid	29a	INH	=	95	%	ALA1641243	%	Aeromonas sp.
9.	6-Fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-1，4-dihydro-[1，3]thiazeto[3，2-a]quinoline-3-carboxylic acid	29a	INH	=	98	%	ALA1641244	%	Aeromonas sp.
10.	6-Fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-1，4-dihydro-[1，3]thiazeto[3，2-a]quinoline-3-carboxylic acid	29a	INH	=	98	%	ALA1641245	%	Aeromonas sp.
11.	6-Fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-1，4-dihydro-[1，3]thiazeto[3，2-a]quinoline-3-carboxylic acid	29a	INH	=	98	%	ALA1641246	%	Aeromonas sp.
12.	6-Fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-1，4-dihydro-[1，3]thiazeto[3，2-a]quinoline-3-carboxylic acid	29a	INH	=	100	%	ALA1641247	%	Aeromonas sp.
13.	ALA1440	Tetracycline	MIC	>=	8	ug ml-1	ALA1633507	ug.mL-1	Aeromonas sp.
14.	ALA1440	Tetracycline	MIC	<=	4	ug ml-1	ALA1633506	ug.mL-1	Aeromonas sp.
15.	ticarcillin	ticarcillin	MIC	=	128	ug ml-1	ALA1281191	ug.mL-1	Aeromonas sp.
16.	Amoxicillin	amoxicilln	MIC	=	8	ug ml-1	ALA1281191	ug.mL-1	Aeromonas sp.
17.	Imipenem	Imipenem	MIC	=	0.25	ug ml-1	ALA1281188	ug.mL-1	Aeromonas sp.
18.	Cefepime	82(Cefepime)	MIC	=	4	ug ml-1	ALA1281188	ug.mL-1	Aeromonas sp.
19.	Cefotaxime acid	cefotaxime	MIC	>	32	ug ml-1	ALA1281188	ug.mL-1	Aeromonas sp.
20.	Ceftazidime (containing approximately 10% sodium carbonate)	CAZ	MIC	>	256	ug ml-1	ALA1281188	ug.mL-1	Aeromonas sp.

1.

6-Fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-1，4-dihydro-[1，3]thiazeto[3，2-a]quinoline-3-carboxylic acid

29a

INH

=

16

%

ALA1641081

%

Aeromonas sp.

2.

6-Fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-1，4-dihydro-[1，3]thiazeto[3，2-a]quinoline-3-carboxylic acid

29a

INH

=

55

%

ALA1641082

%

Aeromonas sp.

3.

6-Fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-1，4-dihydro-[1，3]thiazeto[3，2-a]quinoline-3-carboxylic acid

29a

INH

=

68

%

ALA1641083

%

Aeromonas sp.

4.

6-Fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-1，4-dihydro-[1，3]thiazeto[3，2-a]quinoline-3-carboxylic acid

29a

INH

=

78

%

ALA1641084

%

Aeromonas sp.

5.

6-Fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-1，4-dihydro-[1，3]thiazeto[3，2-a]quinoline-3-carboxylic acid

29a

INH

=

87

%

ALA1641085

%

Aeromonas sp.

6.

6-Fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-1，4-dihydro-[1，3]thiazeto[3，2-a]quinoline-3-carboxylic acid

29a

INH

=

92

%

ALA1641241

%

Aeromonas sp.

7.

6-Fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-1，4-dihydro-[1，3]thiazeto[3，2-a]quinoline-3-carboxylic acid

29a

INH

=

93

%

ALA1641242

%

Aeromonas sp.

8.

6-Fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-1，4-dihydro-[1，3]thiazeto[3，2-a]quinoline-3-carboxylic acid

29a

INH

=

95

%

ALA1641243

%

Aeromonas sp.

9.

6-Fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-1，4-dihydro-[1，3]thiazeto[3，2-a]quinoline-3-carboxylic acid

29a

INH

=

98

%

ALA1641244

%

Aeromonas sp.

10.

6-Fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-1，4-dihydro-[1，3]thiazeto[3，2-a]quinoline-3-carboxylic acid

29a

INH

=

98

%

ALA1641245

%

Aeromonas sp.

11.

6-Fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-1，4-dihydro-[1，3]thiazeto[3，2-a]quinoline-3-carboxylic acid

29a

INH

=

98

%

ALA1641246

%

Aeromonas sp.

12.

6-Fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-1，4-dihydro-[1，3]thiazeto[3，2-a]quinoline-3-carboxylic acid

29a

INH

=

100

%

ALA1641247

%

Aeromonas sp.

13.

ALA1440

Tetracycline

MIC

>=

8

ug ml-1

ALA1633507

ug.mL-1

Aeromonas sp.

14.

ALA1440

Tetracycline

MIC

<=

4

ug ml-1

ALA1633506

ug.mL-1

Aeromonas sp.

15.

ticarcillin

ticarcillin

MIC

=

128

ug ml-1

ALA1281191

ug.mL-1

Aeromonas sp.

16.

Amoxicillin

amoxicilln

MIC

=

8

ug ml-1

ALA1281191

ug.mL-1

Aeromonas sp.

17.

Imipenem

Imipenem

MIC

=

0.25

ug ml-1

ALA1281188

ug.mL-1

Aeromonas sp.

18.

Cefepime

82(Cefepime)

MIC

=

4

ug ml-1

ALA1281188

ug.mL-1

Aeromonas sp.

19.

Cefotaxime acid

cefotaxime

MIC

>

32

ug ml-1

ALA1281188

ug.mL-1

Aeromonas sp.

20.

Ceftazidime (containing approximately 10% sodium carbonate)

CAZ

MIC

>

256

ug ml-1

ALA1281188

ug.mL-1

Aeromonas sp.