# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA511832 | 12 | LD50 | = | 22 | ug ml-1 | ALA5245902 | ug ml-1 | Leishmania braziliensis | |||
2. | ALA511832 | 12 | LD50 | = | 29 | ug ml-1 | ALA5245902 | ug ml-1 | Leishmania braziliensis | |||
3. | ALA511832 | 12 | LD50 | = | 60 | ug ml-1 | ALA5245888 | ug ml-1 | Leishmania braziliensis | |||
4. | ALA511832 | 12 | LD50 | = | 23.2 | ug ml-1 | ALA5245888 | ug ml-1 | Leishmania braziliensis | |||
5. | Miltefosine | Miltefosine | IC50 | = | 10.4 | uM | ALA5245888 | 4.98 | nM | Leishmania braziliensis | ||
6. | ALA5286539 | 11 | IC50 | = | 21.5 | uM | ALA5245888 | 4.67 | nM | Leishmania braziliensis | ||
7. | ALA5274216 | 10 | IC50 | = | 32.1 | uM | ALA5245888 | 4.49 | nM | Leishmania braziliensis | ||
8. | Scopoletin | 2 | IC50 | > | 50 | uM | ALA5245888 | nM | Leishmania braziliensis | |||
9. | 6,7-Dimethoxycoumarin | 56 | IC50 | > | 50 | uM | ALA5245888 | nM | Leishmania braziliensis | |||
10. | ALA5285910 | 56 | IC50 | = | 8.1 | uM | ALA5224580 | 5.09 | nM | Leishmania braziliensis | ||
11. | ALA3127725 | 17 | IC50 | = | 17.3 | uM | ALA5215015 | 4.76 | nM | Leishmania braziliensis | ||
12. | ALA4217754 | 15 | Ratio IC50 | = | 10 | ALA4367794 | Leishmania braziliensis | |||||
13. | Miltefosine | Miltefosine | IC50 | = | 0.89 | uM | ALA4367791 | 6.05 | nM | Leishmania braziliensis | ||
14. | Amphotericin B | amphotericin B | IC50 | = | 0.2 | uM | ALA4367791 | 6.70 | nM | Leishmania braziliensis | ||
15. | ALA4217754 | 15 | IC50 | = | 0.5 | uM | ALA4367791 | 6.30 | nM | Leishmania braziliensis | ||
16. | Miltefosine | Miltefosine | IC50 | = | 7.59 | uM | ALA4367790 | 5.12 | nM | Leishmania braziliensis | ||
17. | Amphotericin B | amphotericin B | IC50 | = | 0.183 | uM | ALA4367790 | 6.74 | nM | Leishmania braziliensis | ||
18. | ALA4217754 | 15 | IC50 | = | 0.38 | uM | ALA4367790 | 6.42 | nM | Leishmania braziliensis | ||
19. | ALA4590410 | 5a | Activity | 0 | ALA4313934 | Active | Leishmania braziliensis | |||||
20. | ALA4529540 | 5c | Activity | 0 | ALA4313934 | Active | Leishmania braziliensis |