| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA2440737 | 32 | Activity | 0 | ALA2443763 | Active | Oryctolagus cuniculus | |||||
| 2. | ALA2440737 | 32 | Activity | = | 0.5 | % | ALA2443763 | % | Oryctolagus cuniculus | |||
| 3. | ALA2440737 | 32 | Activity | = | 28.7 | % | ALA2443762 | % | Oryctolagus cuniculus | |||
| 4. | ALA2440737 | 32 | Activity | 0 | ALA2443761 | Non-toxic | Oryctolagus cuniculus | |||||
| 5. |  ALA2409314 | 6 | EC50 | = | 570 | nM | ALA2412510 | 6.24 | nM | Oryctolagus cuniculus | ||
| 6. | ALA2409314 | 6 | Activity | 0 | ALA2412509 | Non-toxic | Oryctolagus cuniculus | |||||
| 7. |  zavegepant | 3, BMS-742413 | Tmax | = | 15 | min | ALA2400611 | hr | Oryctolagus cuniculus | |||
| 8. | zavegepant | 3, BMS-742413 | F | = | 13 | % | ALA2400609 | % | Oryctolagus cuniculus | |||
| 9. | zavegepant | 3, BMS-742413 | F | = | 30 | % | ALA2400608 | % | Oryctolagus cuniculus | |||
| 10. | zavegepant | 3, BMS-742413 | Cmax | = | 0.12 | uM | ALA2400607 | nM | Oryctolagus cuniculus | |||
| 11. |  1-Butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide | Bupivacaine | Time | = | 94 | min | ALA2389120 | hr | Oryctolagus cuniculus | |||
| 12. |  Ropivacaine base | Ropivacaine | Time | = | 58.4 | min | ALA2389120 | hr | Oryctolagus cuniculus | |||
| 13. |  ALA79 | 1 | Time | = | 37.8 | min | ALA2389120 | hr | Oryctolagus cuniculus | |||
| 14. |  ALA2386868 | cyclomecaine | Time | = | 124.5 | min | ALA2389120 | hr | Oryctolagus cuniculus | |||
| 15. |  ALA2386867 | 4p, diastereomeic mixture | Time | = | 41.3 | min | ALA2389120 | hr | Oryctolagus cuniculus | |||
| 16. |  ALA2386866 | 4o, diastereomeic mixture | Time | = | 73.2 | min | ALA2389120 | hr | Oryctolagus cuniculus | |||
| 17. |  ALA2386865 | 4n, diastereomeic mixture | Time | = | 46.5 | min | ALA2389120 | hr | Oryctolagus cuniculus | |||
| 18. |  ALA2386863 | 4l, diastereomeic mixture | Time | = | 75.7 | min | ALA2389120 | hr | Oryctolagus cuniculus | |||
| 19. |  ALA2386862 | 4k, diastereomeic mixture | Time | = | 59.8 | min | ALA2389120 | hr | Oryctolagus cuniculus | |||
| 20. |  ALA2386859 | 4h, diastereomeic mixture | Time | = | 20.3 | min | ALA2389120 | hr | Oryctolagus cuniculus |
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