Activities

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Activities

Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA5280204	Branched-DAR8	Activity		0		ALA5249738		Not Active		Human immunodeficiency virus 1
2.	ALA5280362	Branched-AR8	Activity		0		ALA5249738		Not Active		Human immunodeficiency virus 1
3.	ALA5281510	AR7	Activity		0		ALA5249738		Not Active		Human immunodeficiency virus 1
4.	ALA5273020	DAR7	Activity		0		ALA5249737		Active		Human immunodeficiency virus 1
5.	ALA5280204	Branched-DAR8	IC50	=	10.87	uM	ALA5249736	4.96		nM	Human immunodeficiency virus 1
6.	ALA5280204	Branched-DAR8	Activity		0		ALA5249735		Active		Human immunodeficiency virus 1
7.	ALA5280362	Branched-AR8	Activity		0		ALA5249735		Active		Human immunodeficiency virus 1
8.	ALA5273020	DAR7	Activity		0		ALA5249735		Active		Human immunodeficiency virus 1
9.	ALA5281510	AR7	Activity		0		ALA5249735		Active		Human immunodeficiency virus 1
10.	ALA89554	64 (+)-beta	EC50	=	0.84	uM	ALA5247124	6.08		nM	Human immunodeficiency virus 1
11.	Emtricitabine	beta-L-SddC (3TC)	EC50	=	8	nM	ALA5247124	8.10		nM	Human immunodeficiency virus 1
12.	ALA18314	SID17389537	EC50	=	0.2	uM	ALA5247124	6.70		nM	Human immunodeficiency virus 1
13.	Lamivudine	3TC	EC50	=	2	uM	ALA5247124	5.70		nM	Human immunodeficiency virus 1
14.	ALA18314	SID17389537	IC50	=	1.22	uM	ALA5247123	5.91		nM	Human immunodeficiency virus 1
15.	Lamivudine	3TC	IC50	=	0.87	uM	ALA5247123	6.06		nM	Human immunodeficiency virus 1
16.	Bictegravir	BICTEGRAVIR	Ratio EC50	=	2		ALA5247097				Human immunodeficiency virus 1
17.	Dolutegravir (GSK1349572)	DOLUTEGRAVIR	Ratio EC50	=	4.8		ALA5247097				Human immunodeficiency virus 1
18.	Bictegravir	BICTEGRAVIR	EC50	=	1.9	nM	ALA5247096	8.72		nM	Human immunodeficiency virus 1
19.	Dolutegravir (GSK1349572)	DOLUTEGRAVIR	EC50	=	1.7	nM	ALA5247096	8.77		nM	Human immunodeficiency virus 1
20.	ALA5281331	71	IC50	=	2.3	uM	ALA5244782	5.64		nM	Human immunodeficiency virus 1