# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | Remdesivir | 4b | EC50 | = | 0.03 | uM | ALA5230475 | 7.52 | nM | Murine hepatitis virus | ||
2. | GS-441524 | 3a | Activity | = | 99.9 | % | ALA5154968 | % | Murine hepatitis virus | |||
3. | GS-441524 | 3a | Activity | = | 99.9 | % | ALA5154967 | % | Murine hepatitis virus | |||
4. | GS-441524 | 3a | Activity | = | 100 | % | ALA5154966 | % | Murine hepatitis virus | |||
5. | GS-441524 | 3a | Activity | = | 100 | % | ALA5154965 | % | Murine hepatitis virus | |||
6. | MPro N3 | N3 | EC50 | = | 3.4 | uM | ALA5137560 | 5.47 | nM | Murine hepatitis virus | ||
7. | MPro N3 | N3 | EC50 | = | 2.7 | uM | ALA5137559 | 5.57 | nM | Murine hepatitis virus | ||
8. | GC376 | 7a | EC50 | = | 1.1 | uM | ALA5124408 | 5.96 | nM | Murine hepatitis virus | ||
9. | ALA5173283 | 9e | EC50 | = | 0.16 | uM | ALA5124408 | 6.80 | nM | Murine hepatitis virus | ||
10. | ALA5175540 | 8e | EC50 | = | 0.2 | uM | ALA5124408 | 6.70 | nM | Murine hepatitis virus | ||
11. | ALA5184284 | 9d | EC50 | = | 0.11 | uM | ALA5124408 | 6.96 | nM | Murine hepatitis virus | ||
12. | ALA5174145 | 8d | EC50 | = | 0.08 | uM | ALA5124408 | 7.10 | nM | Murine hepatitis virus | ||
13. | ALA5188945 | 9c | EC50 | = | 0.13 | uM | ALA5124408 | 6.89 | nM | Murine hepatitis virus | ||
14. | ALA5178275 | 8c | EC50 | = | 0.12 | uM | ALA5124408 | 6.92 | nM | Murine hepatitis virus | ||
15. | ALA5172701 | 9b | EC50 | = | 0.16 | uM | ALA5124408 | 6.80 | nM | Murine hepatitis virus | ||
16. | ALA5194912 | 8b | EC50 | = | 0.13 | uM | ALA5124408 | 6.89 | nM | Murine hepatitis virus | ||
17. | ALA5190394 | 9a | EC50 | = | 0.08 | uM | ALA5124408 | 7.10 | nM | Murine hepatitis virus | ||
18. | ALA5195656 | 8a | EC50 | = | 0.12 | uM | ALA5124408 | 6.92 | nM | Murine hepatitis virus | ||
19. | ALA3249841 | 2 | Activity | = | 37.5 | mg/kg/day | ALA3254585 | mg/kg/day | Murine hepatitis virus | |||
20. | ALA3249841 | 2 | MSD | = | 5.3 | day | ALA3254583 | day | Murine hepatitis virus |