# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2153241 | 31 | Activity | 0 | ALA2154433 | Active | Trypanosoma brucei rhodesiense | |||||
2. | ALA2153117 | 16 | Activity | 0 | ALA2154433 | Active | Trypanosoma brucei rhodesiense | |||||
3. | ALA2153241 | 31 | Activity | 0 | ALA2154432 | Not Active | Trypanosoma brucei rhodesiense | |||||
4. | ALA2153117 | 16 | Activity | 0 | ALA2154432 | Active | Trypanosoma brucei rhodesiense | |||||
5. | ALA2153241 | 31 | MSD | > | 60 | day | ALA2154431 | day | Trypanosoma brucei rhodesiense | |||
6. | ALA2153117 | 16 | MSD | > | 60 | day | ALA2154431 | day | Trypanosoma brucei rhodesiense | |||
7. | ALA2153241 | 31 | MSD | = | 27.75 | day | ALA2154430 | day | Trypanosoma brucei rhodesiense | |||
8. | ALA2153117 | 16 | MSD | > | 60 | day | ALA2154430 | day | Trypanosoma brucei rhodesiense | |||
9. | Difluoromethylornithine | 19 | IC50 | = | 3.8 | uM | ALA2154428 | 5.42 | nM | Trypanosoma brucei rhodesiense | ||
10. | ALA166 | melarsoprol | IC50 | = | 0.009 | uM | ALA2154428 | 8.05 | nM | Trypanosoma brucei rhodesiense | ||
11. | ALA423172 | 6a (Megazol) | IC50 | = | 0.1 | uM | ALA2154428 | 7.00 | nM | Trypanosoma brucei rhodesiense | ||
12. | Fexinidazole | 3 | IC50 | = | 2.57 | uM | ALA2154428 | 5.59 | nM | Trypanosoma brucei rhodesiense | ||
13. | ALA2153259 | 49 | IC50 | = | 23.54 | uM | ALA2154428 | 4.63 | nM | Trypanosoma brucei rhodesiense | ||
14. | ALA2153258 | 48 | IC50 | = | 20.16 | uM | ALA2154428 | 4.70 | nM | Trypanosoma brucei rhodesiense | ||
15. | ALA2153257 | 47 | IC50 | = | 27.03 | uM | ALA2154428 | 4.57 | nM | Trypanosoma brucei rhodesiense | ||
16. | ALA2153256 | 46 | IC50 | = | 124.6 | uM | ALA2154428 | nM | Trypanosoma brucei rhodesiense | |||
17. | ALA2153255 | 45 | IC50 | = | 11.28 | uM | ALA2154428 | 4.95 | nM | Trypanosoma brucei rhodesiense | ||
18. | ALA2153254 | 44 | IC50 | = | 11.89 | uM | ALA2154428 | 4.92 | nM | Trypanosoma brucei rhodesiense | ||
19. | ALA2153253 | 43 | IC50 | = | 95.54 | uM | ALA2154428 | 4.02 | nM | Trypanosoma brucei rhodesiense | ||
20. | ALA2153252 | 42 | IC50 | = | 141.32 | uM | ALA2154428 | nM | Trypanosoma brucei rhodesiense |