Activities

#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay	Assay Organism
1.	6-Fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-1，4-dihydro-[1，3]thiazeto[3，2-a]quinoline-3-carboxylic acid	29a	INH	=	0	%	ALA1641074	%	Yersinia sp.
2.	6-Fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-1，4-dihydro-[1，3]thiazeto[3，2-a]quinoline-3-carboxylic acid	29a	INH	=	0	%	ALA1641075	%	Yersinia sp.
3.	6-Fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-1，4-dihydro-[1，3]thiazeto[3，2-a]quinoline-3-carboxylic acid	29a	INH	=	56	%	ALA1641076	%	Yersinia sp.
4.	6-Fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-1，4-dihydro-[1，3]thiazeto[3，2-a]quinoline-3-carboxylic acid	29a	INH	=	93	%	ALA1641077	%	Yersinia sp.
5.	6-Fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-1，4-dihydro-[1，3]thiazeto[3，2-a]quinoline-3-carboxylic acid	29a	INH	=	93	%	ALA1641078	%	Yersinia sp.
6.	6-Fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-1，4-dihydro-[1，3]thiazeto[3，2-a]quinoline-3-carboxylic acid	29a	INH	=	98	%	ALA1641079	%	Yersinia sp.
7.	6-Fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-1，4-dihydro-[1，3]thiazeto[3，2-a]quinoline-3-carboxylic acid	29a	INH	=	100	%	ALA1641080	%	Yersinia sp.
8.	Imipenem	Imipenem	MIC90	=	0.25	ug ml-1	ALA821045	ug.mL-1	Yersinia sp.
9.	Amoxicillin	amoxicilln	MIC90	>	64	ug ml-1	ALA821045	ug.mL-1	Yersinia sp.
10.	ALA150443	3 (MEN-10700)	MIC90	=	0.5	ug ml-1	ALA821045	ug.mL-1	Yersinia sp.
11.	ALA285269	Ampicillin+Sulbactum	MIC90	=	32	ug ml-1	ALA821045	ug.mL-1	Yersinia sp.
12.	ALA445850	3r	MIC90	=	0.15	ug ml-1	ALA821044	ug.mL-1	Yersinia sp.
13.	Amoxicillin	amoxicilln	MIC90	>	64	ug ml-1	ALA821044	ug.mL-1	Yersinia sp.
14.	ALA132643	3q	MIC90	=	1	ug ml-1	ALA821044	ug.mL-1	Yersinia sp.
15.	ALA2112728	3d(S)	MIC90	=	0.5	ug ml-1	ALA821044	ug.mL-1	Yersinia sp.
16.	ALA435788	3p	MIC90	=	0.25	ug ml-1	ALA821044	ug.mL-1	Yersinia sp.
17.	ALA134453	3a	MIC90	=	0.5	ug ml-1	ALA821044	ug.mL-1	Yersinia sp.

1.

6-Fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-1，4-dihydro-[1，3]thiazeto[3，2-a]quinoline-3-carboxylic acid

29a

INH

=

0

%

ALA1641074

%

Yersinia sp.

2.

6-Fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-1，4-dihydro-[1，3]thiazeto[3，2-a]quinoline-3-carboxylic acid

29a

INH

=

0

%

ALA1641075

%

Yersinia sp.

3.

6-Fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-1，4-dihydro-[1，3]thiazeto[3，2-a]quinoline-3-carboxylic acid

29a

INH

=

56

%

ALA1641076

%

Yersinia sp.

4.

6-Fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-1，4-dihydro-[1，3]thiazeto[3，2-a]quinoline-3-carboxylic acid

29a

INH

=

93

%

ALA1641077

%

Yersinia sp.

5.

6-Fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-1，4-dihydro-[1，3]thiazeto[3，2-a]quinoline-3-carboxylic acid

29a

INH

=

93

%

ALA1641078

%

Yersinia sp.

6.

6-Fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-1，4-dihydro-[1，3]thiazeto[3，2-a]quinoline-3-carboxylic acid

29a

INH

=

98

%

ALA1641079

%

Yersinia sp.

7.

6-Fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-1，4-dihydro-[1，3]thiazeto[3，2-a]quinoline-3-carboxylic acid

29a

INH

=

100

%

ALA1641080

%

Yersinia sp.

8.

Imipenem

Imipenem

MIC90

=

0.25

ug ml-1

ALA821045

ug.mL-1

Yersinia sp.

9.

Amoxicillin

amoxicilln

MIC90

>

64

ug ml-1

ALA821045

ug.mL-1

Yersinia sp.

10.

ALA150443

3 (MEN-10700)

MIC90

=

0.5

ug ml-1

ALA821045

ug.mL-1

Yersinia sp.

11.

ALA285269

Ampicillin+Sulbactum

MIC90

=

32

ug ml-1

ALA821045

ug.mL-1

Yersinia sp.

12.

ALA445850

3r

MIC90

=

0.15

ug ml-1

ALA821044

ug.mL-1

Yersinia sp.

13.

Amoxicillin

amoxicilln

MIC90

>

64

ug ml-1

ALA821044

ug.mL-1

Yersinia sp.

14.

ALA132643

3q

MIC90

=

1

ug ml-1

ALA821044

ug.mL-1

Yersinia sp.

15.

ALA2112728

3d(S)

MIC90

=

0.5

ug ml-1

ALA821044

ug.mL-1

Yersinia sp.

16.

ALA435788

3p

MIC90

=

0.25

ug ml-1

ALA821044

ug.mL-1

Yersinia sp.

17.

ALA134453

3a

MIC90

=

0.5

ug ml-1

ALA821044

ug.mL-1

Yersinia sp.