| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA1255794 | Aplaviroc, GW-873140 | Activity | 0 | ALA1261969 | Non-toxic | Cercopithecidae | |||||
| 2. |  ALA35920 | 4 | Activity | = | 24.4 | % | ALA855607 | % | Cercopithecidae | |||
| 3. |  ALA386709 | 3, (S)-5'-(HO)-DADFT | Activity | = | 12.6 | % | ALA855607 | % | Cercopithecidae | |||
| 4. |  ALA214850 | 4, (S)-5'-(CH3O)-DADFT | Activity | = | 18.9 | % | ALA855607 | % | Cercopithecidae | |||
| 5. |  ALA11300 | 5 | Activity | = | 25.4 | % | ALA855607 | % | Cercopithecidae | |||
| 6. |  ALA35919 | 3 | Activity | = | 16.2 | % | ALA855607 | % | Cercopithecidae | |||
| 7. |  ALA214611 | 9, (S)-5'-(HO)-DADMDFT | Activity | = | 1.8 | % | ALA855607 | % | Cercopithecidae | |||
| 8. |  ALA214958 | 10, (S)-5'-(CH3O)-DADMDFT | Activity | = | 12 | % | ALA855607 | % | Cercopithecidae | |||
| 9. |  ALA214959 | 11, (S)-3',4'-(CH3O)2-DADMDFT | Activity | = | 12.4 | % | ALA855607 | % | Cercopithecidae | |||
| 10. |  ALA432481 | 2 | Activity | = | 16.8 | % | ALA855607 | % | Cercopithecidae | |||
| 11. |  ALA437341 | 25, ABT-341 | F | = | 54 | % | ALA856704 | % | Cercopithecidae | |||
| 12. | ALA437341 | 25, ABT-341 | Vss | = | 3.2 | L/Kg | ALA856703 | L.kg-1 | Cercopithecidae | |||
| 13. | ALA437341 | 25, ABT-341 | T1/2 | = | 6.3 | hr | ALA856702 | hr | Cercopithecidae | |||
| 14. | ALA437341 | 25, ABT-341 | T1/2 | = | 4.3 | hr | ALA856701 | hr | Cercopithecidae | |||
| 15. | ALA437341 | 25, ABT-341 | Tmax | = | 2.7 | hr | ALA856700 | hr | Cercopithecidae | |||
| 16. | ALA437341 | 25, ABT-341 | Cmax | = | 345 | ng/ml | ALA856699 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Cercopithecidae | ||
| 17. | ALA437341 | 25, ABT-341 | AUC | = | 1905 | ng.hr/g | ALA856698 | ng.hr/g | Cercopithecidae | |||
| 18. | ALA437341 | 25, ABT-341 | AUC | = | 3557 | ng.hr/g | ALA856697 | ng.hr/g | Cercopithecidae | |||
| 19. |  Boceprevir | 70 | F | = | 4 | % | ALA910588 | % | Cercopithecidae | |||
| 20. | Boceprevir | 70 | AUC | = | 0.12 | uM.hr | ALA910584 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Cercopithecidae |
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