Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	omidenepag	OMIDENEPAG	EC50	=	8.3	nM	ALA5242757	8.08		nM	Macaca mulatta
2.	ALA5198665	19	EC50	=	20	nM	ALA5133269	7.70		nM	Macaca mulatta
3.	MK-8931	VERUBECESTAT	EC50	=	41	nM	ALA5133269	7.39		nM	Macaca mulatta
4.	ALA3937515	BDBM209918	EC50	=	23	nM	ALA5133269	7.64		nM	Macaca mulatta
5.	ALA5198665	19	ED50	<	3	mg kg-1	ALA5133268			mg.kg-1	Macaca mulatta
6.	MK-8931	VERUBECESTAT	ED50	<	3	mg kg-1	ALA5133268			mg.kg-1	Macaca mulatta
7.	ALA3937515	BDBM209918	ED50	=	0.3	mg kg-1	ALA5133268			mg.kg-1	Macaca mulatta
8.	ALA5183317	12	FC	>	3		ALA5130289				Macaca mulatta
9.	ALA5183317	12	FC	=	2		ALA5130280				Macaca mulatta
10.	Liraglutide	LIRAGLUTIDE	Activity		0		ALA5130271		NA		Macaca mulatta
11.	ALA5183317	12	Activity		0		ALA5130270		Active		Macaca mulatta
12.	Liraglutide	LIRAGLUTIDE	Activity		0		ALA5130269		NA		Macaca mulatta
13.	ALA5183317	12	Activity	=	9.6		ALA5130268				Macaca mulatta
14.	ALA5183317	12	Activity	=	50	%	ALA5130267			%	Macaca mulatta
15.	ALA5183317	12	Activity	=	63	%	ALA5130266			%	Macaca mulatta
16.	ALA5183317	12	FC	=	4		ALA5130265				Macaca mulatta
17.	Liraglutide	LIRAGLUTIDE	Activity		0		ALA5130264		NA		Macaca mulatta
18.	ALA5183317	12	FC	>	3		ALA5130263				Macaca mulatta
19.	Liraglutide	LIRAGLUTIDE	Activity	=	30	mg/dl	ALA5130262			mg/dl	Macaca mulatta
20.	ALA5183317	12	Activity		0		ALA5130261		Active		Macaca mulatta