# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5092803 | SR-9-1d | INH | 0 | ALA5237355 | Not Active | % | Homo sapiens | ||||
2. | ALA5284556 | 11a | INH | 0 | ALA5237355 | Active | % | Homo sapiens | ||||
3. | ALA5079973 | SR-7-2d | INH | 0 | ALA5237355 | Active | % | Homo sapiens | ||||
4. | Captopril | Captopril | IC50 | = | 6.3 | nM | ALA5229316 | 8.20 | nM | Homo sapiens | ||
5. | Rentiapril | 5 | Ki | = | 2.2 | nM | ALA5229289 | 8.66 | nM | Homo sapiens | ||
6. | Rentiapril | 5 | IC50 | = | 6 | nM | ALA5229289 | 8.22 | nM | Homo sapiens | ||
7. | Captopril | Captopril | IC50 | = | 30 | nM | ALA5229289 | 7.52 | nM | Homo sapiens | ||
8. | Rentiapril | 5 | pIC50 | = | 7.55 | ALA5229289 | 7.55 | nM | Homo sapiens | |||
9. | ALA5272875 | 70 | pIC50 | = | 6.08 | ALA5229289 | 6.08 | nM | Homo sapiens | |||
10. | ALA445830 | SA 291 | pIC50 | = | 6.43 | ALA5229289 | 6.43 | nM | Homo sapiens | |||
11. | Captopril | Captopril | pIC50 | = | 6.68 | ALA5229289 | 6.68 | nM | Homo sapiens | |||
12. | ALA5220968 | MLN-4760-S/R | Imax | = | 22 | % | ALA5216077 | % | Homo sapiens | |||
13. | ALA5220314 | MLN-4760-R | Imax | = | 20 | % | ALA5216077 | % | Homo sapiens | |||
14. | MLN-4760 | MLN-4760 | Imax | = | 34 | % | ALA5216077 | % | Homo sapiens | |||
15. | ALA5220968 | MLN-4760-S/R | pIC50 | = | 4.4 | ALA5216075 | 4.40 | nM | Homo sapiens | |||
16. | ALA5220314 | MLN-4760-R | pIC50 | = | 4.4 | ALA5216075 | 4.40 | nM | Homo sapiens | |||
17. | MLN-4760 | MLN-4760 | pIC50 | = | 5 | ALA5216075 | 5.00 | nM | Homo sapiens | |||
18. | ALA5220968 | MLN-4760-S/R | Imax | = | 48 | % | ALA5216073 | % | Homo sapiens | |||
19. | ALA5220314 | MLN-4760-R | Imax | = | 49 | % | ALA5216073 | % | Homo sapiens | |||
20. | MLN-4760 | MLN-4760 | Imax | = | 46 | % | ALA5216073 | % | Homo sapiens |