Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA3417525	69, BI665915	% Ctrl		105	%	ALA4881736		Not Active	%	Homo sapiens
2.	ALA3659677	BDBM98561	IC50	=	26	nM	ALA3705279	7.58	214689	nM	Homo sapiens
3.	ALA3659676	BDBM98560	IC50	=	7.5	nM	ALA3705279	8.12	214688	nM	Homo sapiens
4.	ALA3659675	BDBM98559	IC50	=	38	nM	ALA3705279	7.42	214687	nM	Homo sapiens
5.	ALA3659674	BDBM98558	IC50	=	1.2	nM	ALA3705279	8.92	214686	nM	Homo sapiens
6.	pentobarbitone	pentobarbital	IC50	=	1	mM	ALA2168415			nM	Homo sapiens
7.	pentobarbitone	pentobarbital	INH	>=	90	%	ALA2167735			%	Homo sapiens
8.	ALA2163548	R-(-)-14	INH	>=	90	%	ALA2167729			%	Homo sapiens
9.	ALA2163548	R-(-)-14	IC50	=	3.8	uM	ALA2168415	5.42		nM	Homo sapiens
10.	ALA2163549	S-(+)-14	INH	=	60	%	ALA2167735			%	Homo sapiens
11.	ALA2163549	S-(+)-14	IC50	=	120	uM	ALA2168415			nM	Homo sapiens
12.	MLN8054	MLN-8054	IC50	=	330	nM	ALA3586973	6.48		nM	Homo sapiens
13.	ALA3586473	9	IC50	=	150	nM	ALA3586973	6.82		nM	Homo sapiens
14.	Alisertib (MLN8237)	9, MLN-8237	IC50	=	490	nM	ALA3586973	6.31		nM	Homo sapiens
15.	Flumazenil	31, Ro-151788	pKi	=	9.1		ALA4837570	9.10		nM	Homo sapiens
16.	Pemigatinib	PEMIGATINIB	INH		0		ALA4810230		Not Active	%	Homo sapiens
17.	ALA4744361	26	Efficacy	=	3	%	ALA4701849			%	Homo sapiens
18.	ALA4785872	12	Efficacy	=	32	%	ALA4701849			%	Homo sapiens
19.	ALA4800521	25	Efficacy	=	1	%	ALA4701849			%	Homo sapiens
20.	ALA4785991	23	Efficacy	=	15	%	ALA4701849			%	Homo sapiens