Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	racemic-tofacitinib	CP-690550	Drug uptake	=	22.14	pmol	ALA1657317			pmol	Mus musculus
2.	TCS 21311	1	Drug uptake	=	64.33	pmol	ALA1657317			pmol	Mus musculus
3.	racemic-tofacitinib	CP-690550	Drug uptake	=	10.41	pmol	ALA1657316			pmol	Mus musculus
4.	TCS 21311	1	Drug uptake	=	31.27	pmol	ALA1657316			pmol	Mus musculus
5.	racemic-tofacitinib	CP-690550	Drug uptake	=	3.05	pmol	ALA1657315			pmol	Mus musculus
6.	TCS 21311	1	Drug uptake	=	10.97	pmol	ALA1657315			pmol	Mus musculus
7.	racemic-tofacitinib	CP-690550	Drug uptake	=	1.19	pmol	ALA1657314			pmol	Mus musculus
8.	TCS 21311	1	Drug uptake	=	3.12	pmol	ALA1657314			pmol	Mus musculus
9.	ALA199705	14	IC50	=	3.39	uM	ALA862994	5.47		nM	Mus musculus
10.	ALA200016	12	IC50	=	9.09	uM	ALA862994	5.04		nM	Mus musculus
11.	ALA380570	10	IC50	=	8.1	uM	ALA862994	5.09		nM	Mus musculus
12.	ALA197867	8	IC50	=	7.61	uM	ALA862994	5.12		nM	Mus musculus
13.	ALA199706	6	IC50	=	8.1	uM	ALA862994	5.09		nM	Mus musculus
14.	ALA197819	7	IC50	>	20	uM	ALA862994			nM	Mus musculus
15.	ALA199594	9	IC50	>	20	uM	ALA862994			nM	Mus musculus
16.	ALA197918	11	IC50	>	20	uM	ALA862994			nM	Mus musculus
17.	ALA381672	13	IC50	=	17.5	uM	ALA862994	4.76		nM	Mus musculus
18.	ALA199292	5	IC50	>	20	uM	ALA862994			nM	Mus musculus
19.	ALA198075	(-)-2	IC50		0		ALA862994		Not Determined		Mus musculus
20.	Dolastatin 15	dolastatin 15	IC50	=	3	nM	ALA653485	8.52		nM	Mus musculus