| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  (4aR,7aS)-2-amino-7a-(2,4-difluorophenyl)-6-(5-fluoro-4-methoxy-6-methylpyrimidin-2-yl)-3-methyl-5,7-dihydro-4aH-pyrrolo[3,4-d]pyrimidin-4-one | BDBM9488 | Papp | = | 41 | 10'-6 cm/s | ALA3803588 | 10'-6 cm/s | Canis lupus familiaris | |||
| 2. | (4aR,7aS)-2-amino-7a-(2,4-difluorophenyl)-6-(5-fluoro-4-methoxy-6-methylpyrimidin-2-yl)-3-methyl-5,7-dihydro-4aH-pyrrolo[3,4-d]pyrimidin-4-one | BDBM9488 | Ratio | > | 30 | ALA3803587 | Canis lupus familiaris | |||||
| 3. |  ALA3799200 | 34 | IC50 | = | 149 | uM | ALA3803036 | nM | Canis lupus familiaris | |||
| 4. | ALA3799200 | 34 | IC50 | = | 70.2 | uM | ALA3802770 | 4.15 | nM | Canis lupus familiaris | ||
| 5. |  ALA3799213 | 46; GNE-0723 | Ratio | = | 1.1 | ALA3801526 | Canis lupus familiaris | |||||
| 6. |  ALA3799878 | 45 | Ratio | = | 5.3 | ALA3801526 | Canis lupus familiaris | |||||
| 7. |  ALA3799437 | 44 | Ratio | = | 1 | ALA3801526 | Canis lupus familiaris | |||||
| 8. |  ALA3800556 | 43 | Ratio | = | 1.3 | ALA3801526 | Canis lupus familiaris | |||||
| 9. |  ALA3800605 | 42 | Ratio | = | 0.51 | ALA3801526 | Canis lupus familiaris | |||||
| 10. |  ALA3799064 | 41 | Ratio | = | 3.6 | ALA3801526 | Canis lupus familiaris | |||||
| 11. |  ALA3800265 | 40 | Ratio | = | 0.8 | ALA3801526 | Canis lupus familiaris | |||||
| 12. |  ALA3799657 | 39 | Ratio | = | 1.2 | ALA3801526 | Canis lupus familiaris | |||||
| 13. |  ALA3799233 | 38 | Ratio | = | 3.7 | ALA3801526 | Canis lupus familiaris | |||||
| 14. |  ALA3799759 | 37 | Ratio | = | 57 | ALA3801526 | Canis lupus familiaris | |||||
| 15. |  ALA3797897 | 36 | Ratio | = | 2.2 | ALA3801526 | Canis lupus familiaris | |||||
| 16. |  ALA3799694 | 35 | Ratio | = | 11 | ALA3801526 | Canis lupus familiaris | |||||
| 17. |  ALA3799438 | 34 | Ratio | = | 33 | ALA3801526 | Canis lupus familiaris | |||||
| 18. |  ALA3797392 | 33 | Ratio | = | 21.5 | ALA3801526 | Canis lupus familiaris | |||||
| 19. |  ALA3799181 | 32 | Ratio | = | 2.2 | ALA3801526 | Canis lupus familiaris | |||||
| 20. |  ALA3799814 | 31 | Ratio | = | 44 | ALA3801526 | Canis lupus familiaris |
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