Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA148758	27	GI50	=	1.6	uM	ALA5245622			nM	Homo sapiens
2.	Piperlongumine	3	IC50	=	9.2	uM	ALA5241685	5.04		nM	Homo sapiens
3.	ALA5276508	40	IC50	=	0.6	uM	ALA5241685	6.22		nM	Homo sapiens
4.	PF-06873600	PF-06873600	TGI	=	103	%	ALA5236967			%	Homo sapiens
5.	PF-06873600	PF-06873600	TGI	=	93	%	ALA5236966			%	Homo sapiens
6.	ALA301982	1	IC50	=	1.48	uM	ALA5233880	5.83		nM	Homo sapiens
7.	KPT 330	SELINEXOR	IC50	=	25	nM	ALA5232642	7.60		nM	Homo sapiens
8.	(5S)-5-ethyl-5-hydroxy-7,18,20-trioxa-11,24-diazahexacyclo[11.11.0.02,11.04,9.015,23.017,21]tetracosa-1(13),2,4(9),14,16,21,23-heptaene-6,10-dione	2	EC50	=	1	nM	ALA5227925	9.00		nM	Homo sapiens
9.	BLU-945	BLU-945	Activity		0		ALA5141269		Active		Homo sapiens
10.	ALA1631706	6c	GI50	>	50	uM	ALA4405105			nM	Homo sapiens
11.	ALA4452311	42	LC50	=	39.02	uM	ALA4320822			nM	Homo sapiens
12.	ALA4452311	42	TGI	=	8.17	uM	ALA4320822			nM	Homo sapiens
13.	ALA4452311	42	GI50	=	0.28	uM	ALA4320822			nM	Homo sapiens
14.	ALA4465637	41	LC50	=	64.68	uM	ALA4320822			nM	Homo sapiens
15.	ALA4465637	41	TGI	=	18.11	uM	ALA4320822			nM	Homo sapiens
16.	ALA4465637	41	GI50	=	2.67	uM	ALA4320822			nM	Homo sapiens
17.	ALA4543594	38	LC50	=	97.49	uM	ALA4320822			nM	Homo sapiens
18.	ALA4543594	38	TGI	=	65.57	uM	ALA4320822			nM	Homo sapiens
19.	ALA4543594	38	GI50	=	6.72	uM	ALA4320822			nM	Homo sapiens
20.	ALA4566972	37	LC50	=	91.41	uM	ALA4320822			nM	Homo sapiens