# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | NI 42 | 15; Nl-42 | GI50 | = | 1 | uM | ALA4053032 | nM | Homo sapiens | |||
2. | MB710 | MB710; 70 | IC50 | = | 120 | uM | ALA4154042 | nM | Homo sapiens | |||
3. | ALA4166006 | MB725; 72 | IC50 | > | 120 | uM | ALA4154042 | nM | Homo sapiens | |||
4. | ALA4168439 | 60 | IC50 | = | 159 | uM | ALA4154042 | nM | Homo sapiens | |||
5. | PhiKan 083 | 12 | IC50 | = | 9 | uM | ALA4154042 | 5.05 | nM | Homo sapiens | ||
6. | ALA4163657 | PK7088; 2 | IC50 | > | 120 | uM | ALA4154042 | nM | Homo sapiens | |||
7. | ALA4170894 | PK5196; 3 | IC50 | = | 9 | uM | ALA4154042 | 5.05 | nM | Homo sapiens | ||
8. | ALA4166006 | MB725; 72 | Activity | > | 80 | % | ALA4154050 | % | Homo sapiens | |||
9. | ALA5177476 | 1131-MMAE | Activity | 0 | ALA5109806 | Active | Homo sapiens | |||||
10. | ALA5177476 | 1131-MMAE | Activity | 0 | ALA5109801 | Active | Homo sapiens | |||||
11. | MonoMethyl auristatin E | MMAE | Activity | = | 28.75 | ALA5109779 | Homo sapiens | |||||
12. | ALA5177476 | 1131-MMAE | Activity | = | 87 | ALA5109779 | Homo sapiens | |||||
13. | ALA5177476 | 1131-MMAE | Activity | 0 | ALA5109771 | Active | Homo sapiens | |||||
14. | ALA5177476 | 1131-MMAE | INH | 0 | ALA5109768 | Active | % | Homo sapiens | ||||
15. | ALA5177476 | 1131-MMAE | Activity | 0 | ALA5109765 | Tde | Homo sapiens | |||||
16. | ALA5177476 | 1131-MMAE | Activity | = | 67.4 | % | ALA5109762 | % | Homo sapiens | |||
17. | ALA5177476 | 1131-MMAE | Activity | = | 49.53 | % | ALA5109761 | % | Homo sapiens | |||
18. | ALA5177476 | 1131-MMAE | Activity | = | 30.9 | % | ALA5109760 | % | Homo sapiens | |||
19. | MonoMethyl auristatin E | MMAE | IC50 | = | 10.97 | nM | ALA5109755 | 7.96 | nM | Homo sapiens | ||
20. | ALA5196075 | Table 1, R1C2 | IC50 | 0 | ALA5109755 | ND | Homo sapiens |