Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	pyrotinib	PYROTINIB	IC50	=	60.8	nM	ALA5162345	7.22		nM	Homo sapiens
2.	Neratinib (HKI-272)	25o (table 3)	IC50	=	38.15	nM	ALA5162345	7.42		nM	Homo sapiens
3.	ALA5178703	17	IC50	=	1218.72	nM	ALA5162345	5.91		nM	Homo sapiens
4.	MB710	MB710; 70	IC50	=	120	uM	ALA4154042			nM	Homo sapiens
5.	ALA4166006	MB725; 72	IC50	>	120	uM	ALA4154042			nM	Homo sapiens
6.	ALA4168439	60	IC50	=	159	uM	ALA4154042			nM	Homo sapiens
7.	PhiKan 083	12	IC50	=	9	uM	ALA4154042	5.05		nM	Homo sapiens
8.	ALA4163657	PK7088; 2	IC50	>	120	uM	ALA4154042			nM	Homo sapiens
9.	ALA4170894	PK5196; 3	IC50	=	9	uM	ALA4154042	5.05		nM	Homo sapiens
10.	ALA4166006	MB725; 72	Activity	>	80	%	ALA4154050			%	Homo sapiens
11.	ALA5268484	11; GNE-375	IC50	=	2	uM	ALA5262247	5.70		nM	Homo sapiens
12.	ALA5270178	5	IC50	=	20	uM	ALA5262247	4.70		nM	Homo sapiens
13.	ALA5282240	3	IC50	=	20	uM	ALA5262247	4.70		nM	Homo sapiens
14.	NI 42	15; Nl-42	GI50	=	1	uM	ALA4053032			nM	Homo sapiens
15.	ALA5177476	1131-MMAE	Activity		0		ALA5109806		Active		Homo sapiens
16.	ALA5177476	1131-MMAE	Activity		0		ALA5109801		Active		Homo sapiens
17.	MMAE	MMAE	Activity	=	28.75		ALA5109779				Homo sapiens
18.	ALA5177476	1131-MMAE	Activity	=	87		ALA5109779				Homo sapiens
19.	ALA5177476	1131-MMAE	Activity		0		ALA5109771		Active		Homo sapiens
20.	ALA5177476	1131-MMAE	INH		0		ALA5109768		Active	%	Homo sapiens